Recombinant
RabMAb

Recombinant Anti-IL-26 antibody [EPR6745] - BSA and Azide free (ab232180)

Overview

  • Product name

    Anti-IL-26 antibody [EPR6745] - BSA and Azide free
    See all IL-26 primary antibodies
  • Description

    Rabbit monoclonal [EPR6745] to IL-26 - BSA and Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human IL-26 aa 100 to the C-terminus. The exact sequence is proprietary.
    Database link: Q9NPH9

  • Positive control

    • WB: Recombinant Human IL26 protein with a proprietary tag.
  • General notes

    ab232180 is the carrier-free version of ab133659 This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.

    Use our conjugation kits  for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    Ab232180 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.

    Maxpar® is a trademark of Fluidigm Canada Inc.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Constituent: PBS
  • Concentration information loading...
  • Purity

    Affinity purified
  • Clonality

    Monoclonal
  • Clone number

    EPR6745
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab232180 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Detects a band of approximately 20 kDa (predicted molecular weight: 20 kDa).

Target

  • Function

    May play a role in local mechanisms of mucosal immunity and seems to have a proinflammatory function. May play a role in inflammatory bowel disease. Activates STAT1 and STAT3, MAPK1/3 (ERK1/2), JUN and AKT. Induces expression of SOCS3, TNF-alpha and IL-8, secretion of IL-8 and IL-10 and surface expression of ICAM1. Decreases proliferation of intestinal epithelial cells. Is inhibited by heparin.
  • Tissue specificity

    Expressed in HVS transformed T-cells but not other T-cell lines or primary stimulated T-cells. Expressed in colonic T cells including Th17 inflammatory T cells; the expression is significantly increased in serum of patients with Crohn's disease (at protein level).
  • Sequence similarities

    Belongs to the IL-10 family.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • AK155 antibody
    • IL 26 antibody
    • IL-26 antibody
    • IL26 antibody
    • IL26_HUMAN antibody
    • Interleukin 26 antibody
    • Interleukin-26 antibody
    • Protein AK155 antibody
    see all

Images

  • Anti-IL-26 antibody [EPR6745] (ab133659) at 1/1000 dilution + Recombinant Human IL26 protein with a proprietary tag at 0.01 µg

    Secondary
    HRP labeled goat anti-rabbit at 1/2000 dilution

    Predicted band size: 20 kDa



    This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA, glycerol, and sodium azide (ab133659).

References

ab232180 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab232180.
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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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