Recombinant
RabMAb

Recombinant Anti-IL-28 + IL-29 antibody [EPR14608] (HRP) (ab209048)

Overview

  • Product name

    Anti-IL-28 + IL-29 antibody [EPR14608] (HRP)
    See all IL-28 + IL-29 primary antibodies
  • Description

    Rabbit monoclonal [EPR14608] to IL-28 + IL-29 (HRP)
  • Host species

    Rabbit
  • Conjugation

    HRP
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human IL-28 + IL-29 aa 50-150. The exact sequence is proprietary.
    Database link: Q8IZJ0

  • Positive control

    • WB: Human IL28A full length (Active) protein.
  • General notes

     

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab209048 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/10000. Detects a band of approximately 20 kDa (predicted molecular weight: 22 kDa).

Target

  • Relevance

    IL-29: Cytokine with immunomodulatory activity. May play a role in antiviral immunity. Up-regulates MHC class I antigen expression. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Il-28A: Cytokine with immunomodulatory activity. Up-regulates MHC class I antigen expression. Displays potent antiviral activity. Also displays antitumor activity. Ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1. The ligand/receptor complex seems to signal through the Jak-STAT pathway. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium.
  • Cellular localization

    Secreted.
  • Database links

  • Alternative names

    • IFNL1 antibody
    • IFNL2 antibody
    • Cytokine Zcyto20 antibody
    • Cytokine Zcyto21 antibody
    • Cytokine Zcyto22 antibody
    • IFN-lambda-1 antibody
    • IFN-lambda-2 antibody
    • IFNL3 antibody
    • IL-28A antibody
    • IL-28B antibody
    • IL-28C antibody
    • IL28 + IL29 antibody
    • IL28A antibody
    • IL28B antibody
    • IL28C antibody
    • IL29 antibody
    • Interferon lambda-1 antibody
    • Interferon lambda-2 antibody
    • Interferon lambda-3 antibody
    • Interleukin-28A antibody
    • Interleukin-28B antibody
    • Interleukin-28C antibody
    • Interleukin-29 antibody
    • ZCYTO20 antibody
    • ZCYTO21 antibody
    • ZCYTO22 antibody
    see all

Images

  • Anti-IL-28 + IL-29 antibody [EPR14608] (HRP) (ab209048) at 1/10000 dilution + Recombinant human IL-28A protein (ab50037) at 0.1 µg

    Developed using the ECL technique.

    Performed under reducing conditions.

    Predicted band size: 22 kDa
    Observed band size: 20 kDa
    why is the actual band size different from the predicted?


    Exposure time: 10 seconds


    This blot was produced using a 4-12% Bis-tris gel under the MES buffer system. The gel was run at 200V for 35 minutes before being transferred onto a Nitrocellulose membrane at 30V for 70 minutes. The membrane was then blocked for an hour using 3% milk before being incubated with ab209048 overnight at 4°C. Antibody binding was visualised using ECL development solution ab133406.

References

ab209048 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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