Key features and details
- Rabbit polyclonal to IL-31
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Rat
- Isotype: IgG
Product nameAnti-IL-31 antibody
See all IL-31 primary antibodies
DescriptionRabbit polyclonal to IL-31
Specificityab37157 recognises Interleukin 31 (IL31).
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Mouse, Rat
Synthetic peptide corresponding to Mouse IL-31 (N terminal).
(Peptide available as
- RAW264.7 cell lysate
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferPreservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab37157 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 2.5 - 5 µg/ml. Detects a band of approximately 30 kDa (predicted molecular weight: 18 kDa).|
|IHC-P||Use a concentration of 10 µg/ml.|
FunctionActivates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity.
Tissue specificityDetected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea.
- Information by UniProt
FormAmino acids 1-23 are a signal peptide.
- IL 31 antibody
- IL-31 antibody
- IL31 antibody
Lane 1 : Anti-IL-31 antibody (ab37157) at 2.5 µg/ml
Lane 2 : Anti-IL-31 antibody (ab37157) at 5 µg/ml
Lane 3 : Anti-IL-31 antibody (ab37157) at 10 µg/ml
All lanes : RAW264.7 cell lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 18 kDa
Observed band size: 30 kDa why is the actual band size different from the predicted?
ab37157 at 10µg/ml staining IL-31 in rat skeletal muscle tissue by IHC
ab37157 has been referenced in 1 publication.
- Niyonsaba F et al. Antimicrobial peptides human beta-defensins and cathelicidin LL-37 induce the secretion of a pruritogenic cytokine IL-31 by human mast cells. J Immunol 184:3526-34 (2010). PubMed: 20190140