FormLyophilised:Reconstitute in sterile PBS containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: None
Constituents: PBS, pH 7.2
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab84241 was purified by affinity chromatography and then biotinylated and filter sterilised.
Our Abpromise guarantee covers the use of ab84241 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
sELISA: Use at a concentration of 0.25 - 1 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant Human IL31.
WB: Use at a concentration of 0.1 - 0.2 µg/ml. The detection limit for recombinant Human IL31 is 1.5 - 3.0 ng/lane under either reducing or non-reducing conditions. Predicted molecular weight: 18 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionActivates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity.
Tissue specificityDetected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea.
- Information by UniProt
FormAmino acids 1-23 are a signal peptide.
- IL 31 antibody
- IL-31 antibody
- IL31 antibody
ab84241 has not yet been referenced specifically in any publications.