Overview

Properties

  • Form

    Lyophilised:Reconstitute in sterile PBS containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml.
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    ab84241 was purified by affinity chromatography and then biotinylated and filter sterilised.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab84241 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Sandwich ELISA
WB
  • Application notes
    ELISA: Use at a concentration of 0.25 - 1 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant Human IL31.
    sELISA: Use at a concentration of 0.25 - 1 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant Human IL31.
    WB: Use at a concentration of 0.1 - 0.2 µg/ml. The detection limit for recombinant Human IL31 is 1.5 - 3.0 ng/lane under either reducing or non-reducing conditions. Predicted molecular weight: 18 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Function

      Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity.
    • Tissue specificity

      Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea.
    • Cellular localization

      Secreted.
    • Information by UniProt
    • Database links

    • Form

      Amino acids 1-23 are a signal peptide.
    • Alternative names

      • IL 31 antibody
      • IL-31 antibody
      • IL31 antibody
      • IL31_HUMAN antibody
      • Interleukin 31 antibody
      • Interleukin-31 antibody
      see all

    References

    ab84241 has not yet been referenced specifically in any publications.

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