Overview

  • Product name

  • Description

    Rabbit polyclonal to IL-31RA
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Recombinant fragment corresponding to Human IL-31RA aa 91-378.

  • Positive control

    • Jurkat whole cell lysate (ab7899), Human fetal liver, fetal kidney, fetal spleen and fetal colon lysates; Human fetal prostate tissue.

Properties

Applications

Our Abpromise guarantee covers the use of ab113498 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/1000. Predicted molecular weight: 83 kDa.
IHC-P 1/100 - 1/500.

Target

  • Function

    Associates with OSMR to form the interleukin-31 receptor which activates STAT3 and to a lower extent STAT1 and STAT5. May function in skin immunity.
  • Tissue specificity

    Expressed at low levels in testis, ovary, brain, prostate, placenta, thymus, bone marrow, trachea and skin. Detected in all of the myelomonocytic lineage. Expressed in CD14-and CD56-positive blood cells and by macrophages (at protein level).
  • Sequence similarities

    Belongs to the type I cytokine receptor family. Type 2 subfamily.
    Contains 5 fibronectin type-III domains.
  • Post-translational
    modifications

    N-glycosylated.
  • Cellular localization

    Cell membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Class I cytokine receptor antibody
    • CRL 3 antibody
    • CRL antibody
    • CRL3 antibody
    • Cytokine receptor like 3 antibody
    • Cytokine receptor-like 3 antibody
    • GLM R antibody
    • GLM-R antibody
    • GLMR antibody
    • Gp130 like monocyte receptor antibody
    • GP130 like receptor antibody
    • Gp130-like monocyte receptor antibody
    • Gp130-like receptor antibody
    • GPL antibody
    • HGLM R antibody
    • HGLM-R antibody
    • HGLMR antibody
    • IL 31 receptor subunit alpha antibody
    • IL 31R subunit alpha antibody
    • IL 31RA antibody
    • IL-31 receptor subunit alpha antibody
    • IL-31R subunit alpha antibody
    • IL-31R-alpha antibody
    • IL-31RA antibody
    • IL31 receptor subunit alpha antibody
    • IL31R subunit alpha antibody
    • IL31R_HUMAN antibody
    • IL31RA antibody
    • Interleukin 31 receptor A antibody
    • interleukin 31 receptor subunit alpha antibody
    • Interleukin-31 receptor subunit alpha antibody
    • MGC125346 antibody
    • PLCA 2 antibody
    • PLCA2 antibody
    • PRO21384 antibody
    • Soluble type I cytokine receptor CRL3 antibody
    • ZcytoR17 antibody
    see all

Images

  • All lanes : Anti-IL-31RA antibody (ab113498) at 1/500 dilution

    Lane 1 : Jurkat cell lysate
    Lane 2 : Human fetal liver lysate
    Lane 3 : Human fetal kidney lysate
    Lane 4 : Human fetal spleen lysate
    Lane 5 : Human fetal colon lysate

    Predicted band size: 83 kDa

  • ab113498, at 1/100, staining IL31RA in Formalin-fixed, Paraffin-embedded Human fetal prostate tissue by Immunohistochemistry.

References

ab113498 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

1-2 of 2 Abreviews or Q&A

Answer

Thank you for contacting us. The Abreview has been published so the discount is OK to use. I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.

Read More
Abreviews
Application
Western blot
Sample
Mouse Tissue lysate - whole (liver, brain, bone merrow)
Loading amount
125 µg
Specification
liver, brain, bone merrow
Treatment
Folfox for 24h and control (Not treated)
Gel Running Conditions
Reduced Denaturing (4-15)
Blocking step
Milk as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 20% · Temperature: 24°C

Dr. Ella Fremder

Verified customer

Submitted Nov 16 2011

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