Key features and details
- Rabbit polyclonal to IL-34
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-IL-34 antibody
See all IL-34 primary antibodies
DescriptionRabbit polyclonal to IL-34
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Recombinant full length protein corresponding to Human IL-34 aa 21-242. (BC029804)
- Human fetal spleen tissue; Human fetal brain lysate.
Previously labelled as Interleukin 34.
FormLyophilized:Reconstitute with 200ul distilled sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: PBS, 1% BSA
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab111978 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Detects a band of approximately 48 kDa (predicted molecular weight: 27 kDa).|
FunctionCytokine that promotes the differentiation and viability of monocytes and macrophages. Stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. Ligand for colony-stimulating factor-1 receptor CSF1R.
Tissue specificityDetected in the sinusoidal epithelium in the red pulp of spleen (at protein level). Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon.
Sequence similaritiesBelongs to the IL-34 family.
- Information by UniProt
- C16orf77 antibody
- Chromosome 16 open reading frame 77 antibody
- FPT025 antibody
ab111978 has been referenced in 1 publication.
- Ciccia F et al. IL-34 is overexpressed in the inflamed salivary glands of patients with Sjogren's syndrome and is associated with the local expansion of pro-inflammatory CD14brightCD16+ monocytes. Rheumatology (Oxford) 52:1009-17 (2013). IHC-P ; Human . PubMed: 23392590