Overview

  • Product name

  • Description

    Rabbit polyclonal to IL-36R
  • Host species

    Rabbit
  • Specificity

    ab180894 will detect all three isoforms of IL1RL2. ab180894 is predicted to not cross-react with IL1 Receptor I or ST2.
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide corresponding to Human IL-36R (internal sequence). (16 amino acid peptide; NP_003845).
    Database link: Q9HB29

  • Positive control

    • Human small intestine lysate and tissue.
  • General notes

     This product was previously labelled as IL-1RL2

     

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab180894 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 5 - 20 µg/ml.
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 65 kDa).

Target

  • Function

    Receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B.
  • Sequence similarities

    Belongs to the interleukin-1 receptor family.
    Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 TIR domain.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • IL 1 receptor related protein 2 antibody
    • IL 1Rrp2 antibody
    • IL 36R antibody
    • IL-1Rrp2 antibody
    • IL-36 receptor antibody
    • IL1 receptor related protein 2 antibody
    • IL1R rp2 antibody
    • IL1R-rp2 antibody
    • Il1rl2 antibody
    • IL1RRP2 antibody
    • IL36R antibody
    • ILRL2_HUMAN antibody
    • Interleukin 1 receptor like 2 antibody
    • Interleukin 1 receptor related protein 2 antibody
    • Interleukin-1 receptor-like 2 antibody
    • Interleukin-1 receptor-related protein 2 antibody
    see all

Images

  • Lane 1 : Anti-IL-36R antibody (ab180894) at 1 µg/ml
    Lane 2 : Anti-IL-36R antibody (ab180894) at 2 µg/ml

    All lanes : Human small intestine lysate

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 65 kDa
    Observed band size: 55 kDa
    why is the actual band size different from the predicted?

  • Immunohistochemical analysis of paraffin-embedded Human small intestine tissue labeling IL1RL2 with ab180894 at 5 μg/ml.

  • Immunohistochemical analysis of paraffin-embedded Human small intestine tissue labeling IL1RL2 with ab180894 at 20 µg/ml.

References

This product has been referenced in:

  • Russell SE  et al. IL-36a expression is elevated in ulcerative colitis and promotes colonic inflammation. Mucosal Immunol 9:1193-204 (2016). Read more (PubMed: 26813344) »
See 1 Publication for this product

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There are currently no Customer reviews or Questions for ab180894.
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