Key features and details
- Rabbit polyclonal to IL-36R
- Suitable for: IHC-P, WB
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-IL-36R antibody
See all IL-36R primary antibodies
DescriptionRabbit polyclonal to IL-36R
Specificityab180894 will detect all three isoforms of IL1RL2. ab180894 is predicted to not cross-react with IL1 Receptor I or ST2.
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Rat, Human
Synthetic peptide corresponding to Human IL-36R (internal sequence). (16 amino acid peptide; NP_003845).
Database link: Q9HB29
- Human small intestine lysate and tissue.
This product was previously labelled as IL-1RL2
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab180894 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 5 - 20 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 65 kDa).|
FunctionReceptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B.
Sequence similaritiesBelongs to the interleukin-1 receptor family.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 TIR domain.
- Information by UniProt
- IL 1 receptor related protein 2 antibody
- IL 1Rrp2 antibody
- IL 36R antibody
Lane 1 : Anti-IL-36R antibody (ab180894) at 1 µg/ml
Lane 2 : Anti-IL-36R antibody (ab180894) at 2 µg/ml
All lanes : Human small intestine lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 65 kDa
Observed band size: 55 kDa why is the actual band size different from the predicted?
Immunohistochemical analysis of paraffin-embedded Human small intestine tissue labeling IL1RL2 with ab180894 at 5 μg/ml.
Immunohistochemical analysis of paraffin-embedded Human small intestine tissue labeling IL1RL2 with ab180894 at 20 µg/ml.
ab180894 has been referenced in 1 publication.
- Russell SE et al. IL-36a expression is elevated in ulcerative colitis and promotes colonic inflammation. Mucosal Immunol 9:1193-204 (2016). PubMed: 26813344