Overview

  • Product name

    Anti-IL-3RB antibody - C-terminal
    See all IL-3RB primary antibodies
  • Description

    Rabbit polyclonal to IL-3RB - C-terminal
  • Host species

    Rabbit
  • Specificity

    ab198701 detects endogenous level of total IL3RB protein.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human IL-3RB (C terminal). The exact sequence is proprietary. NCBI Accession No. NP_000386.
    Database link: P32927

  • Positive control

    • Human cervical cancer and ovarian cancer tissues.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.3
    Preservative: 0.05% Sodium azide
    Constituents: 50% Glycerol, 49% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab198701 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/40 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor.
  • Sequence similarities

    Belongs to the type I cytokine receptor family. Type 4 subfamily.
    Contains 2 fibronectin type-III domains.
  • Domain

    The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is required for JAK interaction and/or activation.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Beta-C antibody
    • CD131 antibody
    • CDw131 antibody
    • Colony stimulating factor 2 receptor beta antibody
    • Colony stimulating factor 2 receptor beta low affinity (granulocyte macrophage) antibody
    • Common beta chain antibody
    • Csf2rb antibody
    • Cytokine receptor common beta chain antibody
    • Cytokine receptor common beta chain precursor (CDw131 antigen) antibody
    • Cytokine receptor common subunit beta antibody
    • GM CSF/IL 3/IL 5 receptor common beta chain antibody
    • GM-CSF/IL-3/IL-5 receptor common beta subunit antibody
    • granulocyte-macrophage colony-stimulating factor receptor, beta antibody
    • IL3RB antibody
    • IL3RB_HUMAN antibody
    • IL5RB antibody
    • Interleukin 3 receptor, beta antibody
    • Interleukin 3 receptor/granulocyte macrophage colony stimulating factor 3 receptor beta (high affinity) antibody
    • Interleukin 5 receptor, beta antibody
    • SMDP5 antibody
    • stimulating factor 3 receptor, beta (high affinity) antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue labeling IL3RB using ab198701 at a 1/40 dilution.

  • Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue labeling IL3RB using ab198701 at a 1/40 dilution.

References

ab198701 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab198701.
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