Recombinant
RabMAb

Recombinant Anti-IL-5RA antibody [EPR5450(2)] (ab134935)

Overview

  • Product name

    Anti-IL-5RA antibody [EPR5450(2)]
    See all IL-5RA primary antibodies
  • Description

    Rabbit monoclonal [EPR5450(2)] to IL-5RA
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: IHC-P or IP
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human IL-5RA aa 350-450 (C terminal). The exact sequence is proprietary.

  • Positive control

    • Human platelet and serum lysates.
  • General notes

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

     

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at -20ºC.
  • Storage buffer

    Preservative: 0.01% Sodium azide
    Constituents: 9% PBS, 40% Glycerol, 0.05% BSA, 50% Tissue culture supernatant
  • Purity

    Tissue culture supernatant
  • Clonality

    Monoclonal
  • Clone number

    EPR5450(2)
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab134935 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Predicted molecular weight: 48 kDa.
  • Application notes
    Is unsuitable for IHC-P or IP.
  • Target

    • Function

      This is the receptor for interleukin-5. The alpha chain binds to IL5.
    • Tissue specificity

      Expressed on eosinophils and basophils.
    • Sequence similarities

      Belongs to the type I cytokine receptor family. Type 5 subfamily.
    • Domain

      The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
      The box 1 motif is required for JAK interaction and/or activation.
    • Cellular localization

      Membrane.
    • Information by UniProt
    • Database links

    • Alternative names

      • CD125 antibody
      • CD125 antigen antibody
      • CDw125 antibody
      • HSIL5R3 antibody
      • IL-5 receptor subunit alpha antibody
      • IL-5R subunit alpha antibody
      • IL-5R-alpha antibody
      • IL-5RA antibody
      • IL5R antibody
      • IL5RA antibody
      • IL5RA_HUMAN antibody
      • Interleukin 5 Receptor alpha antibody
      • Interleukin 5 Receptor alpha chain antibody
      • Interleukin 5 receptor alpha subunit antibody
      • Interleukin 5 receptor subunit alpha antibody
      • Interleukin 5 receptor type 3 antibody
      • Interleukin-5 receptor subunit alpha antibody
      • MGC26560 antibody
      see all

    Images

    • All lanes : Anti-IL-5RA antibody [EPR5450(2)] (ab134935) at 1/1000 dilution

      Lane 1 : Human platelet lysate
      Lane 2 : Human serum lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : Standard HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 48 kDa

    References

    ab134935 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    There are currently no Customer reviews or Questions for ab134935.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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