Anti-IL-6 antibody (ab9324)

Mouse monoclonal IL-6 antibody. Validated in WB, IHC, Neut, ICC/IF, sELISA and tested in Rat, Human. Cited in 58 publication(s). Independently reviewed in 8 review(s).

Publishing research using ab9324? Please let us know so that we can cite the reference in this datasheet.

ab9324 has been referenced in 64 publications.

  • Dormer NH  et al. Evaluation of a transtympanic delivery system in Mus musculus for extended release steroids. Eur J Pharm Sci 126:3-10 (2019). PubMed: 29329746
  • Jitmana R  et al. Role of cardiac mast cells in exercise training-mediated cardiac remodeling in angiotensin II-infused ovariectomized rats. Life Sci 219:209-218 (2019). PubMed: 30658099
  • Zhang G  et al. Resveratrol alleviates lipopolysaccharide-induced inflammation in PC-12 cells and in rat model. BMC Biotechnol 19:10 (2019). PubMed: 30691440
  • McLean K  et al. Leukemia inhibitory factor functions in parallel with interleukin-6 to promote ovarian cancer growth. Oncogene 38:1576-1584 (2019). PubMed: 30305729
  • Zheng C  et al. Low-intensity pulsed ultrasound attenuates cardiac inflammation of CVB3-induced viral myocarditis via regulation of caveolin-1 and MAPK pathways. J Cell Mol Med 23:1963-1975 (2019). PubMed: 30592150
  • Zhong W  et al. Human bone marrow-derived mesenchymal stem cells promote the growth and drug-resistance of diffuse large B-cell lymphoma by secreting IL-6 and elevating IL-17A levels. J Exp Clin Cancer Res 38:73 (2019). PubMed: 30755239
  • Salvo E  et al. Reciprocal interactions between cancer and Schwann cells contribute to oral cancer progression and pain. Heliyon 5:e01223 (2019). PubMed: 30815600
  • Yajima R  et al. Mechanism of fibrogenesis in submandibular glands in patients with IgG4-RD. J Mol Histol 49:577-587 (2018). PubMed: 30251185
  • Cummins CB  et al. Antifibrosis Effect of Novel Oridonin Analog CYD0618 Via Suppression of the NF-?B Pathway. J Surg Res 232:283-292 (2018). PubMed: 30463731
  • Yao Y  et al. PSTPIP2 Inhibits the Inflammatory Response and Proliferation of Fibroblast-Like Synoviocytes in vitro. Front Pharmacol 9:1432 (2018). PubMed: 30564127
  • Yu B  et al. Morroniside on anti-inflammation activities in rats following acute myocardial infarction. Korean J Physiol Pharmacol 22:17-21 (2018). PubMed: 29302208
  • Moroi H  et al. The expression of Toll-like receptor 5 in preterm histologic chorioamnionitis. J Clin Biochem Nutr 62:63-67 (2018). PubMed: 29371755
  • Guan L  et al. PM2.5 inhalation induces intracranial atherosclerosis which may be ameliorated by omega 3 fatty acids. Oncotarget 9:3765-3778 (2018). PubMed: 29423081
  • Wang G  et al. Lycorine Suppresses Endplate-Chondrocyte Degeneration and Prevents Intervertebral Disc Degeneration by Inhibiting NF-?B Signalling Pathway. Cell Physiol Biochem 45:1252-1269 (2018). PubMed: 29448253
  • Han CL  et al. LncRNA H19 contributes to hippocampal glial cell activation via JAK/STAT signaling in a rat model of temporal lobe epilepsy. J Neuroinflammation 15:103 (2018). PubMed: 29636074
  • Krasovska V & Doering LC Regulation of IL-6 Secretion by Astrocytes via TLR4 in the Fragile X Mouse Model. Front Mol Neurosci 11:272 (2018). PubMed: 30123107
  • Xiang Q  et al. ISL1 overexpression enhances the survival of transplanted human mesenchymal stem cells in a murine myocardial infarction model. Stem Cell Res Ther 9:51 (2018). PubMed: 29482621
  • Liu Z  et al. Number 2 Feibi Recipe Reduces PM2.5-Induced Lung Injury in Rats. Evid Based Complement Alternat Med 2018:3674145 (2018). PubMed: 29541141
  • Sukumaran V  et al. Ghrelin Pre-treatment Attenuates Local Oxidative Stress and End Organ Damage During Cardiopulmonary Bypass in Anesthetized Rats. Front Physiol 9:196 (2018). PubMed: 29593559
  • Wu H  et al. Whole Body Vibration Retards Progression of Atherosclerosis via Insulin-Like Growth Factor 1 in Apolipoprotein E-Deficient Mice. Biomed Res Int 2018:4934861 (2018). PubMed: 29707570
  • Zhang B  et al. Tanshinone IIA Attenuates Diabetic Peripheral Neuropathic Pain in Experimental Rats via Inhibiting Inflammation. Evid Based Complement Alternat Med 2018:2789847 (2018). PubMed: 29713362
  • Piao X  et al. 1-Deoxynojirimycin (DNJ) Ameliorates Indomethacin-Induced Gastric Ulcer in Mice by Affecting NF-kappaB Signaling Pathway. Front Pharmacol 9:372 (2018). PubMed: 29725297
  • Wang X  et al. Costus root granules improve ulcerative colitis through regulation of TGF-ß mediation of the PI3K/AKT signaling pathway. Exp Ther Med 15:4477-4484 (2018). PubMed: 29731832
  • Zhang Y  et al. Chemerin suppresses neuroinflammation and improves neurological recovery via CaMKK2/AMPK/Nrf2 pathway after germinal matrix hemorrhage in neonatal rats. Brain Behav Immun 70:179-193 (2018). PubMed: 29499303
  • Wadghiri YZ  et al. High-resolution Imaging of Myeloperoxidase Activity Sensors in Human Cerebrovascular Disease. Sci Rep 8:7687 (2018). PubMed: 29769642
  • Yang X  et al. Apolipoprotein E Deficiency Exacerbates Spinal Cord Injury in Mice: Inflammatory Response and Oxidative Stress Mediated by NF-?B Signaling Pathway. Front Cell Neurosci 12:142 (2018). PubMed: 29875635
  • Liu Q  et al. Increased Piezo1 channel activity in interstitial Cajal-like cells induces bladder hyperactivity by functionally interacting with NCX1 in rats with cyclophosphamide-induced cystitis. Exp Mol Med 50:60 (2018). WB ; Rat . PubMed: 29735991
  • Song J  et al. CRISPR/Cas9-mediated knockout of HBsAg inhibits proliferation and tumorigenicity of HBV-positive hepatocellular carcinoma cells. J Cell Biochem N/A:N/A (2018). PubMed: 29904948
  • Loomis Z  et al. Hemoglobin induced cell trauma indirectly influences endothelial TLR9 activity resulting in pulmonary vascular smooth muscle cell activation. PLoS One 12:e0171219 (2017). PubMed: 28152051
  • Han S  et al. LPS alters the immuno-phenotype of glioma and glioma stem-like cells and induces in vivo antitumor immunity via TLR4. J Exp Clin Cancer Res 36:83 (2017). PubMed: 28641579
  • Yin L  et al. Ultraviolet B Inhibits IL-17A/TNF-a-Stimulated Activation of Human Dermal Fibroblasts by Decreasing the Expression of IL-17RA and IL-17RC on Fibroblasts. Front Immunol 8:91 (2017). WB . PubMed: 28217129
  • Mohr T  et al. Proteome profiling in IL-1ß and VEGF-activated human umbilical vein endothelial cells delineates the interlink between inflammation and angiogenesis. PLoS One 12:e0179065 (2017). IF . PubMed: 28617818
  • Li JJ  et al. Biliverdin administration ameliorates cerebral ischemia reperfusion injury in rats and is associated with proinflammatory factor downregulation. Exp Ther Med 14:671-679 (2017). PubMed: 28672984
  • Uzan J  et al. Supervised Clustering of Adipokines and Hormonal Receptors Predict Prognosis in a Population of Obese Women with Type 1 Endometrial Cancer. Int J Mol Sci 18:N/A (2017). PubMed: 28505082
  • Munje RD  et al. A new paradigm in sweat based wearable diagnostics biosensors using Room Temperature Ionic Liquids (RTILs). Sci Rep 7:1950 (2017). PubMed: 28512341
  • Guillot X  et al. Local cryotherapy improves adjuvant-induced arthritis through down-regulation of IL-6 / IL-17 pathway but independently of TNFa. PLoS One 12:e0178668 (2017). PubMed: 28759646
  • Zhang Y  et al. Experimental study of ASCs combined with POC-PLA patch for the reconstruction of full-thickness chest wall defects. PLoS One 12:e0182971 (2017). IHC-P ; Rat . PubMed: 28800620
  • Huang H  et al. Interleukin-6, tumor necrosis factor-alpha and receptor activator of nuclear factor kappa ligand are elevated in hypertrophic gastric mucosa of pachydermoperiostosis. Sci Rep 7:9686 (2017). PubMed: 28851954
  • Sithu SD  et al. Atherogenesis and metabolic dysregulation in LDL receptor-knockout rats. JCI Insight 2:N/A (2017). IHC-P ; Rat . PubMed: 28469073
  • Liu X  et al. Hydrogen coadministration slows the development of COPD-like lung disease in a cigarette smoke-induced rat model. Int J Chron Obstruct Pulmon Dis 12:1309-1324 (2017). WB ; Rat . PubMed: 28496315
  • Zhou J  et al. Interleukin-6 induces an epithelial-mesenchymal transition phenotype in human adamantinomatous craniopharyngioma cells and promotes tumor cell migration. Mol Med Rep 15:4123-4131 (2017). WB, IHC . PubMed: 28487953
  • Müllers E  et al. Residual Cdk1/2 activity after DNA damage promotes senescence. Aging Cell 16:575-584 (2017). PubMed: 28345297
  • Wei CC  et al. Nicotinamide mononucleotide attenuates brain injury after intracerebral hemorrhage by activating Nrf2/HO-1 signaling pathway. Sci Rep 7:717 (2017). IHC . PubMed: 28386082
  • Ramella M  et al. Endothelial MMP-9 drives the inflammatory response in abdominal aortic aneurysm (AAA). Am J Transl Res 9:5485-5495 (2017). PubMed: 29312500
  • Wang N  et al. Depot-specific inflammation with decreased expression of ATM2 in white adipose tissues induced by high-margarine/lard intake. PLoS One 12:e0188007 (2017). PubMed: 29141038
  • Sauter MM & Brandt CR Primate neural retina upregulates IL-6 and IL-10 in response to a herpes simplex vector suggesting the presence of a pro-/anti-inflammatory axis. Exp Eye Res 148:12-23 (2016). PubMed: 27170050
  • Liu M  et al. Hyperamylinemia Increases IL-1ß Synthesis in the Heart via Peroxidative Sarcolemmal Injury. Diabetes 65:2772-83 (2016). PubMed: 27335231
  • Fu Y  et al. Renal-targeting triptolide-glucosamine conjugate exhibits lower toxicity and superior efficacy in attenuation of ischemia/reperfusion renal injury in rats. Acta Pharmacol Sin 37:1467-1480 (2016). PubMed: 27397544
  • Yang M  et al. A Microscopic and Biomarker Evaluation of Embolic Filter Debris Collected During Carotid Artery Stenting. J Endovasc Ther N/A:N/A (2016). PubMed: 26839124
  • Yang N  et al. TNF-a receptor antagonist attenuates isoflurane-induced cognitive impairment in aged rats. Exp Ther Med 12:463-468 (2016). WB ; Rat . PubMed: 27347079
  • Sousa LM  et al. Is the canine corpus luteum an insulin-sensitive tissue? J Endocrinol 231:223-233 (2016). PubMed: 27679426
  • Xue H  et al. A Novel Tumor-promoting Mechanism of IL6 and the Therapeutic Efficacy of Tocilizumab: Hypoxia-induced IL6 Is a Potent Autophagy Initiator in Glioblastoma via the p-STAT3-MIR155-3p-CREBRF Pathway. Autophagy N/A:0 (2016). IHC-P ; Human . PubMed: 27163161
  • König C  et al. Involvement of Spinal IL-6 Trans-Signaling in the Induction of Hyperexcitability of Deep Dorsal Horn Neurons by Spinal Tumor Necrosis Factor-Alpha. J Neurosci 36:9782-91 (2016). IHC-M ; Rat . PubMed: 27656018
  • Oliver RA  et al. Development of a Novel Model for the Assessment of Dead-Space Management in Soft Tissue. PLoS One 10:e0136514 (2015). IHC ; Rabbit . PubMed: 26305692
  • Fraveto A  et al. Sensitivity of Human Intrahepatic Cholangiocarcinoma Subtypes to Chemotherapeutics and Molecular Targeted Agents: A Study on Primary Cell Cultures. PLoS One 10:e0142124 (2015). PubMed: 26571380
  • Cassol E  et al. CD14(+) macrophages that accumulate in the colon of African AIDS patients express pro-inflammatory cytokines and are responsive to lipopolysaccharide. BMC Infect Dis 15:430 (2015). PubMed: 26475133
  • Dell'Ovo V  et al. An animal model for chorioamnionitis at term. Am J Obstet Gynecol 213:387.e1-10 (2015). PubMed: 25979619
  • Garrido M  et al. C-reactive protein expression is up-regulated in apical lesions of endodontic origin in association with interleukin-6. J Endod 41:464-9 (2015). PubMed: 25748492
  • Song L  et al. Antitumor efficacy of the anti-interleukin-6 (IL-6) antibody siltuximab in mouse xenograft models of lung cancer. J Thorac Oncol 9:974-82 (2014). PubMed: 24922005
  • Neher JJ  et al. Phagocytosis executes delayed neuronal death after focal brain ischemia. Proc Natl Acad Sci U S A 110:E4098-107 (2013). WB ; Mouse . PubMed: 24101459
  • Pacal M & Bremner R Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons. Dev Dyn 241:1525-44 (2012). PubMed: 22837015
  • Janssen CE  et al. Morphologic and immunohistochemical characterization of granulomas in the nucleotide oligomerization domain 2-related disorders Blau syndrome and Crohn disease. J Allergy Clin Immunol 129:1076-84 (2012). PubMed: 22464675
  • Messina GA  et al. Microfluidic immunosensor design for the quantification of interleukin-6 in human serum samples. Anal Biochem 380:262-7 (2008). PubMed: 18577366
  • Mertz KD  et al. The IL-33/ST2 pathway contributes to intestinal tumorigenesis in humans and mice. Oncoimmunology 5:e1062966 (0). IHC . PubMed: 26942077

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