Anti-IL1 Receptor I/IL-1R-1 antibody [D1f3] (ab8156)
Key features and details
- Rat monoclonal [D1f3] to IL1 Receptor I/IL-1R-1
- Reacts with: Mouse
- Isotype: IgG1
Overview
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Product name
Anti-IL1 Receptor I/IL-1R-1 antibody [D1f3]
See all IL1 Receptor I/IL-1R-1 primary antibodies -
Description
Rat monoclonal [D1f3] to IL1 Receptor I/IL-1R-1 -
Host species
Rat -
Specificity
Binds to soluble mouse interleukin-1 receptor type I. -
Species reactivity
Reacts with: Mouse -
General notes
The IL-1 system includes two agonists (IL-1 alpha and IL-1 alpha), converting enzymes, antagonists, two receptors (IL-1 RI and IL-1 RII) and the IL-1 receptor accessory protein. Interleukin-1 signal is transduced through the type I receptor.
Previously labelled as IL1 Receptor I.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
Preservative: 0.02% Sodium azide -
Concentration information loading... -
Purity
Protein G purified -
Primary antibody notes
The IL-1 system includes two agonists (IL-1 alpha and IL-1 alpha), converting enzymes, antagonists, two receptors (IL-1 RI and IL-1 RII) and the IL-1 receptor accessory protein. Interleukin-1 signal is transduced through the type I receptor. -
Clonality
Monoclonal -
Clone number
D1f3 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Target
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Function
Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2. -
Sequence similarities
Belongs to the interleukin-1 receptor family.
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 TIR domain. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 16177 Mouse
- SwissProt: P13504 Mouse
- Unigene: 896 Mouse
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Alternative names
- Antigen CD121a antibody
- CD121 antigen-like family member A antibody
- CD121a antibody
see all
Datasheets and documents
References (0)
ab8156 has not yet been referenced specifically in any publications.
