Recombinant
RabMAb

Recombinant Anti-IL1 Receptor I/IL-1R-1 antibody [EPR18693-60] (ab222565)

Overview

  • Product name

    Anti-IL1 Receptor I/IL-1R-1 antibody [EPR18693-60]
    See all IL1 Receptor I/IL-1R-1 primary antibodies
  • Description

    Rabbit monoclonal [EPR18693-60] to IL1 Receptor I/IL-1R-1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: Sandwich ELISAmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • General notes

    Anti-IL-1 Receptor I / IL-1R-1 antibody is used in our 90-minute Human IL-1 Receptor I ELISA Kit (ab211650), and is available in a Matched Antibody Pair Kit (ab210888).

    Previously labelled as IL1 Receptor I. 

Properties

Applications

Our Abpromise guarantee covers the use of ab222565 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Sandwich ELISA Use at an assay dependent concentration.

Target

  • Function

    Receptor for interleukin-1 alpha (IL-1A), beta (IL-1B), and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappa-B. Signaling involves formation of a ternary complex containing IL1RAP, TOLLIP, MYD88, and IRAK1 or IRAK2.
  • Sequence similarities

    Belongs to the interleukin-1 receptor family.
    Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 TIR domain.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • Antigen CD121a antibody
    • CD121 antigen-like family member A antibody
    • CD121a antibody
    • CD121a antigen antibody
    • D2S1473 antibody
    • IL 1 antibody
    • IL 1R 1 antibody
    • IL 1R alpha antibody
    • IL 1RT1 antibody
    • IL-1R-1 antibody
    • IL-1R-alpha antibody
    • IL-1RT-1 antibody
    • IL-1RT1 antibody
    • IL1 inhibitor antibody
    • IL1 Receptor I antibody
    • IL1R antibody
    • IL1R1 antibody
    • IL1R1_HUMAN antibody
    • IL1RA antibody
    • IL1RN antibody
    • IL1RT1 antibody
    • Interleukin 1 receptor alpha type 1 antibody
    • Interleukin 1 receptor antagonist protein (IRAP) antibody
    • Interleukin 1 receptor type I antibody
    • Interleukin receptor 1 antibody
    • Interleukin-1 receptor alpha antibody
    • Interleukin-1 receptor type 1 antibody
    • Interleukin-1 receptor type I antibody
    • p80 antibody
    see all

Images

  • Example of human IL-1 Receptor I/IL-1R-1 standard curve in 1X Cell Extraction Buffer PTR using recombinant IL-1 Receptor I/IL-1R-1 RabMAb antibody (ab222565) and a recombinant monoclonal antibody. Background-subtracted values (mean +/- SD) are graphed.

    For a complete ELISA kit, see Human IL-1 Receptor I ELISA kit (ab211650).

    For a matched antibody pair set, see Human IL-1 Receptor I Matched Antibody Pair Kit (ab210888).

References

ab222565 has not yet been referenced specifically in any publications.

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