Anti-IL-13 receptor alpha 2 antibody (ab108534)
Key features and details
- Rabbit polyclonal to IL-13 receptor alpha 2
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Overview
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Product name
Anti-IL-13 receptor alpha 2 antibody
See all IL-13 receptor alpha 2 primary antibodies -
Description
Rabbit polyclonal to IL-13 receptor alpha 2 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Recombinant fragment corresponding to Human IL-13 receptor alpha 2 aa 72-349.
Database link: BC020739 -
Positive control
- Fetal liver
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Lyophilized:Reconstitute with 200ul distilled sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary. -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Preservative: 0.02% Sodium azide -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab108534 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB | (2) |
1/500 - 1/1000. Predicted molecular weight: 44 kDa.
|
IHC-P |
1/100 - 1/500.
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Notes |
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WB
1/500 - 1/1000. Predicted molecular weight: 44 kDa. |
IHC-P
1/100 - 1/500. |
Target
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Function
Binds as a monomer with high affinity to interleukin-13 (IL13), but not to interleukin-4 (IL4). -
Sequence similarities
Belongs to the type I cytokine receptor family. Type 5 subfamily.
Contains 1 fibronectin type-III domain. -
Domain
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 3598 Human
- Entrez Gene: 16165 Mouse
- Entrez Gene: 171060 Rat
- Omim: 300130 Human
- SwissProt: Q14627 Human
- SwissProt: O88786 Mouse
- SwissProt: Q8VHK6 Rat
- Unigene: 336046 Human
see all -
Alternative names
- Cancer/testis antigen 19 antibody
- CD213a2 antibody
- CT19 antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab108534 has been referenced in 1 publication.
- Li L et al. M2a Macrophage-Secreted CHI3L1 Promotes Extracellular Matrix Metabolic Imbalances via Activation of IL-13Ra2/MAPK Pathway in Rat Intervertebral Disc Degeneration. Front Immunol 12:666361 (2021). PubMed: 34168643