Recombinant Anti-IL-19 antibody [EPNCIR168] (ab154187)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPNCIR168] to IL-19
- Suitable for: WB, ICC/IF
- Reacts with: Mouse, Human
Related conjugates and formulations
Overview
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Product name
Anti-IL-19 antibody [EPNCIR168]
See all IL-19 primary antibodies -
Description
Rabbit monoclonal [EPNCIR168] to IL-19 -
Host species
Rabbit -
Tested applications
Suitable for: WB, ICC/IFmore details
Unsuitable for: IHC-P or IP -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
Full length protein corresponding to Mouse IL-19.
Database link: Q8CJ70 -
Positive control
- Mouse IL19 recombinant protein; U937 cells
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General notes
This antibody was developed as part of a collaboration between the National Cancer Institute's Center for Cancer Research and the lab of Juergen Mueller. View antibodies from NCI Center for Cancer Research Collaboration.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Rat: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at -20ºC. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 9% PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA, 50% Tissue culture supernatant -
Concentration information loading...
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Purity
Tissue culture supernatant -
Clonality
Monoclonal -
Clone number
EPNCIR168 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab154187 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/1000 - 1/10000. Predicted molecular weight: 20 kDa.
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|
ICC/IF |
1/50 - 1/100.
|
Notes |
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WB
1/1000 - 1/10000. Predicted molecular weight: 20 kDa. |
ICC/IF
1/50 - 1/100. |
Target
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Function
May play some important roles in inflammatory responses. Up-regulates IL-6 and TNF-alpha and induces apoptosis. -
Sequence similarities
Belongs to the IL-10 family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 29949 Human
- Entrez Gene: 329244 Mouse
- Omim: 605687 Human
- SwissProt: Q9UHD0 Human
- SwissProt: Q8CJ70 Mouse
- Unigene: 661017 Human
- Unigene: 131480 Mouse
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Alternative names
- IL 10C antibody
- IL 19 antibody
- IL-19 antibody
see all
Images
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (4)
ab154187 has been referenced in 4 publications.
- Wang Y et al. Interleukin-19 Aggravates Pulmonary Fibrosis via Activating Fibroblast through TGF-β/Smad Pathway. Mediators Inflamm 2022:6755407 (2022). PubMed: 35281428
- Le Roux M et al. IL-20 Cytokines Are Involved in Epithelial Lesions Associated with Virus-Induced COPD Exacerbation in Mice. Biomedicines 9:N/A (2021). PubMed: 34944654
- Tao K et al. LncRNA CASC11 improves atherosclerosis by downregulating IL-9 and regulating vascular smooth muscle cell apoptosis and proliferation. Biosci Biotechnol Biochem N/A:1-5 (2019). PubMed: 30915898
- Madouri F et al. Production of Interleukin-20 cytokines limits bacterial clearance and lung inflammation during infection by Streptococcus pneumoniae. EBioMedicine 37:417-427 (2018). PubMed: 30361066