Overview

  • Product name

    Anti-IL2 Receptor beta/p75 antibody
    See all IL2 Receptor beta/p75 primary antibodies
  • Description

    Rabbit polyclonal to IL2 Receptor beta/p75
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Fusion protein within Human IL2 Receptor beta/p75 (internal sequence). The exact sequence is proprietary. Fusion protein corresponding to a region derived from internal residues of human IL2/p75 Receptor beta. The identity of the protein fusion partner is GST.
    Database link: P14784
    (Peptide available as ab228476)

  • Positive control

    • 231, 293T, Raji and HeLa cell lysates; Human thyroid cancer tissue.
  • General notes

     This product was previously labelled as IL2 Receptor beta

     

Properties

Applications

Our Abpromise guarantee covers the use of ab197934 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/25 - 1/100.
WB 1/325 - 1/2000. Predicted molecular weight: 60 kDa.

Target

  • Function

    Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
  • Sequence similarities

    Belongs to the type I cytokine receptor family. Type 4 subfamily.
    Contains 1 fibronectin type-III domain.
  • Domain

    The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is required for JAK interaction and/or activation.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD122 antibody
    • CD122 antigen antibody
    • High affinity IL 2 receptor beta subunit antibody
    • High affinity IL 2 receptor subunit beta antibody
    • High affinity IL-2 receptor subunit beta antibody
    • IL-2 receptor subunit beta antibody
    • IL-2R subunit beta antibody
    • IL-2RB antibody
    • IL15RB antibody
    • IL2 receptor antibody
    • IL2RB antibody
    • IL2RB_HUMAN antibody
    • Interleukin 2 receptor beta antibody
    • Interleukin-2 receptor subunit beta antibody
    • P70 75 antibody
    • P70-75 antibody
    • P7075 antibody
    • p75 antibody
    see all

Images

  • All lanes : Anti-IL2 Receptor beta/p75 antibody (ab197934) at 1/325 dilution

    Lane 1 : 231 cell lysate
    Lane 2 : 293T cell lysate
    Lane 3 : Raji cell lysate
    Lane 4 : HeLa cell lysate

    Lysates/proteins at 40 µg per lane.

    Predicted band size: 60 kDa


    Exposure time: 20 seconds
  • Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling IL2 Receptor beta/p75 with ab197934 at 1/30.

References

ab197934 has not yet been referenced specifically in any publications.

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