Product nameAnti-IL2 Receptor beta/p75 antibody
See all IL2 Receptor beta/p75 primary antibodies
DescriptionRabbit polyclonal to IL2 Receptor beta/p75
ab61195 detects endogenous levels of total IL2 Receptor beta/p75 protein.
Tested applicationsSuitable for: IHC-P, WB, ELISAmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse
Synthetic peptide corresponding to Human IL2 Receptor beta/p75.
- Human lung carcinoma tissue and COS7 cell extracts.
This product was previously labelled as IL2 Receptor beta
Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol, 0.87% Sodium chloride
Without Mg2+ and Ca2+
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab61195 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Our Abpromise guarantee covers the use of ab61195 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/100.|
|WB||1/500 - 1/1000. Detects a band of approximately 61 kDa (predicted molecular weight: 61 kDa).|
FunctionReceptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
Sequence similaritiesBelongs to the type I cytokine receptor family. Type 4 subfamily.
Contains 1 fibronectin type-III domain.
DomainThe WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation.
- Information by UniProt
- CD122 antibody
- CD122 antigen antibody
- High affinity IL 2 receptor beta subunit antibody
ab61195 at 1/50 dilution staining IL2 Receptor beta/p75 in human lung carcinoma by Immunohistochemistry, Paraffin-embedded tissue, in the absence (left) or presence (right) of the immunising peptide.
All lanes : Anti-IL2 Receptor beta/p75 antibody (ab61195) at 1/500 dilution
Lane 1 : COS7 cell extracts
Lane 2 : COS7 cell extracts with immunising peptide
Predicted band size: 61 kDa
Observed band size: 61 kDa
This product has been referenced in:
- Iskandar R et al. Expression of pericardial fluid T-cells and related inflammatory cytokines in patients with chronic heart failure. Exp Ther Med 13:1850-1858 (2017). Read more (PubMed: 28565777) »
- Lu ZH et al. CD25 is a novel marker of hepatic bile canaliculus. Int J Surg Pathol 20:455-61 (2012). ICC/IF ; Human . Read more (PubMed: 22576476) »