Anti-IL2 Receptor beta/p75 antibody [TM-beta1] - BSA and Azide free (ab171228)

Overview

  • Product name

    Anti-IL2 Receptor beta/p75 antibody [TM-beta1] - BSA and Azide free
    See all IL2 Receptor beta/p75 primary antibodies
  • Description

    Rat monoclonal [TM-beta1] to IL2 Receptor beta/p75 - BSA and Azide free
  • Host species

    Rat
  • Tested applications

    Suitable for: Flow Cyt, Functional Studiesmore details
  • Species reactivity

    Reacts with: Mouse
  • Immunogen

    The details of the immunogen for this antibody are not available.

  • Positive control

    • Mouse splenocyte suspensions.
  • General notes

    Endotoxin Level: Less than 0.001 ng/µg antibody, as determined by the LAL assay.

     This product was previously labelled as IL2 Receptor beta

     

Properties

Applications

Our Abpromise guarantee covers the use of ab171228 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
Flow Cyt Use at an assay dependent concentration.

ab18536 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody.

Functional Studies Use 0.5µg for 105-8 cells.

(Final test volume = 100 µL)

Target

  • Function

    Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
  • Sequence similarities

    Belongs to the type I cytokine receptor family. Type 4 subfamily.
    Contains 1 fibronectin type-III domain.
  • Domain

    The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
    The box 1 motif is required for JAK interaction and/or activation.
  • Cellular localization

    Membrane.
  • Information by UniProt
  • Database links

  • Alternative names

    • CD122 antibody
    • CD122 antigen antibody
    • High affinity IL 2 receptor beta subunit antibody
    • High affinity IL 2 receptor subunit beta antibody
    • High affinity IL-2 receptor subunit beta antibody
    • IL-2 receptor subunit beta antibody
    • IL-2R subunit beta antibody
    • IL-2RB antibody
    • IL15RB antibody
    • IL2 receptor antibody
    • IL2RB antibody
    • IL2RB_HUMAN antibody
    • Interleukin 2 receptor beta antibody
    • Interleukin-2 receptor subunit beta antibody
    • P70 75 antibody
    • P70-75 antibody
    • P7075 antibody
    • p75 antibody
    see all

References

ab171228 has not yet been referenced specifically in any publications.

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