Key features and details
- Rabbit polyclonal to IL22 RA2/IL-22BP
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-IL22 RA2/IL-22BP antibody
See all IL22 RA2/IL-22BP primary antibodies
DescriptionRabbit polyclonal to IL22 RA2/IL-22BP
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Recombinant fragment corresponding to Human IL22 RA2/IL-22BP aa 1-208. (NP_851826)
- HeLa S3 whole cell lysate
Protein previously labeled as IL22 RA2.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab96341 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/100 - 1/1000. Predicted molecular weight: 27 kDa.|
FunctionIsoform 2 is a receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses.
Isoform 1 may play a role in establishing and maintaining successful pregnancy.
Tissue specificityExpressed in placenta, spleen, breast, skin and lung. Also detected in intestinal tract, testis, brain, heart and thymus. No expression found in prostate, bladder, kidney, ovary, muscle, bone marrow, liver and uterus. Isoform 1 is expressed only in placenta. Isoform 2 is expressed in placenta and breast and at lower level in spleen, skin, thymus and stomach.
Sequence similaritiesBelongs to the type II cytokine receptor family.
Contains 3 fibronectin type-III domains.
- Information by UniProt
- IL 22BP antibody
- IL 22RA2 antibody
- IL22RA2 antibody
ab96341 has been referenced in 1 publication.
- Reemann P et al. Expression of class II cytokine genes in children's skin. Acta Derm Venereol 94:386-92 (2014). PubMed: 24284923