Product nameAnti-IL28RA antibody
See all IL28RA primary antibodies
DescriptionRabbit polyclonal to IL28RA
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog
- Jurkat cell lysate.
This product was previously labelled as IL-28 Receptor alpha
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferPreservative: 0.09% Sodium azide
Constituents: 2% Sucrose, PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab83865 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 57 kDa.
Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
RelevanceIL-28RA is a class II cytokine receptor that interacts with IL10RB to bind IL28A, IL28B, and IL29, which are related to type I interferons. These ligands play a critical role in response to microbial challenge and activate the JAK/STAT signaling system. It heterodimers with IL10RB. There are 4 isoforms as result of alternative splicing. It is widely expressed. IL-28RA belongs to the type II cytokine receptor family, and contains 1 fibronectin type III domain.
Cellular localizationMembrane; Single-pass type I membrane protein
- Class II cytokine receptor CRF2/12 antibody
- CRF2-12 antibody
- CRF2/12 antibody
Anti-IL28RA antibody (ab83865) at 1 µg/ml (5% skim milk / PBS) + Jurkat cell lysate at 10 µg
HRP conjugated anti-Rabbit IgG at 1/50000 dilution
Predicted band size: 57 kDa
Observed band size: 48 kDa why is the actual band size different from the predicted?
Additional bands at: 35 kDa. We are unsure as to the identity of these extra bands.
This product has been referenced in:
- Tian J et al. Blocking the PI3K/AKT pathway enhances mammalian reovirus replication by repressing IFN-stimulated genes. Front Microbiol 6:886 (2015). Read more (PubMed: 26388843) »
- Reemann P et al. Expression of class II cytokine genes in children's skin. Acta Derm Venereol 94:386-92 (2014). Read more (PubMed: 24284923) »