Overview

  • Product name

    Anti-IL36 beta/IL-1F8 antibody - C-terminal
  • Description

    Rabbit polyclonal to IL36 beta/IL-1F8 - C-terminal
  • Host species

    Rabbit
  • Specificity

    ab180890 will only detect the longer isoform of IL36 beta / IL-1F8. ab180890 will not cross-react with IL36 alpha or IL36 gamma.
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human IL36 beta/IL-1F8 (C terminal). (16 amino acid peptide; NP_055253).
    Database link: Q9NZH7

  • Positive control

    • A549 cell lysate; Human lung tissue.
  • General notes

    Previously labelled as IL36 beta.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    Preservative: 0.02% Sodium azide
    Constituent: 99% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab180890 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 1 - 2 µg/ml. Detects a band of approximately 17 kDa (predicted molecular weight: 19 kDa).
IHC-P Use a concentration of 2.5 - 20 µg/ml.

Target

  • Tissue specificity

    Expression at low levels in tonsil, bone marrow, heart, placenta, lung, testis and colon but not in other tissues or in any hematopoietic cell lines.
  • Sequence similarities

    Belongs to the IL-1 family.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • 2310043N20Rik antibody
    • Family of interleukin 1 eta antibody
    • FIL1 (ETA) antibody
    • FIL1 antibody
    • FIL1 eta antibody
    • FIL1H antibody
    • FILI-(ETA) antibody
    • IL 1F8 (FIL1 eta antibody
    • IL 1F8 antibody
    • IL 1H2 antibody
    • IL-1 eta antibody
    • IL-1F8 antibody
    • IL-1H2 antibody
    • IL1 ETA antibody
    • IL1F8 (Canonical product IL 1F8a) antibody
    • IL1F8 antibody
    • IL1F8_HUMAN antibody
    • IL1H2 antibody
    • IL36 beta antibody
    • IL36B antibody
    • Interleukin 1 family, member 8 (eta) antibody
    • Interleukin 1 family, member 8 antibody
    • Interleukin 1 homolog 2 antibody
    • Interleukin 1 Superfamily e antibody
    • Interleukin 36 beta antibody
    • Interleukin-1 eta antibody
    • Interleukin-1 family member 8 antibody
    • Interleukin-1 homolog 2 antibody
    • MGC126880 antibody
    • MGC126882 antibody
    • OTTMUSP00000012797 antibody
    • RP23-176J12.1 antibody
    see all

Images

  • All lanes : Anti-IL36 beta/IL-1F8 antibody - C-terminal (ab180890) at 1 µg/ml

    Lane 1 : A549 cell lysate
    Lane 2 : A549 cell lysate with blocking peptide

    Lysates/proteins at 15 µg per lane.

    Predicted band size: 19 kDa
    Observed band size: 17 kDa
    why is the actual band size different from the predicted?

  • Immunohistochemical analysis of paraffin-embedded Human lung tissue labeling IL36 beta / IL-1F8 with ab180890 at 2.5 μg/ml.

  • Immunohistochemical analysis of Human lung tissue labeling IL36 beta / IL-1F8 with ab180890 at 20 µg/ml.

References

This product has been referenced in:

  • Frew JW  et al. A systematic review and critical evaluation of inflammatory cytokine associations in hidradenitis suppurativa. F1000Res 7:1930 (2018). Read more (PubMed: 30828428) »
See 1 Publication for this product

Customer reviews and Q&As

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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