ab157332 recognizes IL3RA expressed by myeloid precursors, megakaryocytes, macrophages, dendritic cells, mast cells, basophils, and some B cells. This antibody does not inhibit IL-3 binding to its receptor.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use 4µl for 106 cells.
Use 4µl per 100µl of whole blood. The content of a vial (0.4 ml) is sufficient for 100 tests.
ab157226 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
This is a receptor for interleukin-3.
Belongs to the type I cytokine receptor family. Type 5 subfamily.
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding. The box 1 motif is required for JAK interaction and/or activation.