Anti-IL-3RB antibody [RM0112-42A7] (ab86743)
Key features and details
- Rat monoclonal [RM0112-42A7] to IL-3RB
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG1
Overview
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Product name
Anti-IL-3RB antibody [RM0112-42A7]
See all IL-3RB primary antibodies -
Description
Rat monoclonal [RM0112-42A7] to IL-3RB -
Host species
Rat -
Specificity
This antibody detects mouse IL3RB, but not IL3RA in Western blotting. -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Recombinant fragment corresponding to Mouse IL-3RB aa 1-450.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
Storage buffer
Constituent: PBS -
Concentration information loading...
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Purity
Protein A purified -
Purification notes
The IgG fraction of culture supernatant was purified by Protein A affinity chromatography -
Clonality
Monoclonal -
Clone number
RM0112-42A7 -
Isotype
IgG1 -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab86743 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
Use at an assay dependent concentration.
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Notes |
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WB
Use at an assay dependent concentration. |
Target
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Function
High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor. -
Sequence similarities
Belongs to the type I cytokine receptor family. Type 4 subfamily.
Contains 2 fibronectin type-III domains. -
Domain
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 12983 Mouse
- SwissProt: P26955 Mouse
- Unigene: 235324 Mouse
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Alternative names
- Beta-C antibody
- CD131 antibody
- CDw131 antibody
see all
Datasheets and documents
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Datasheet download
References (1)
ab86743 has been referenced in 1 publication.
- Egea L et al. GM-CSF produced by nonhematopoietic cells is required for early epithelial cell proliferation and repair of injured colonic mucosa. J Immunol 190:1702-13 (2013). PubMed: 23325885