Overview

  • Product name

    Imetit dihydrobromide, H3 and H4 receptor agonist
  • Description

    Highly potent H3 and H4 receptor agonist
  • Biological description

    Highly potent H3 and H4 receptor agonist (Ki values are 0.3 and 2.7 nM, respectively). Centrally active following systemic administration. Displays various biological activities.
  • CAS Number

    32385-58-3
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Parsons ME & Ganellin CR Histamine and its receptors. Br J Pharmacol 147 Suppl 1:S127-35 (2006). Read more (PubMed: 16402096) »
  • Kathmann M  et al. Nordimaprit, homodimaprit, clobenpropit and imetit: affinities for H3 binding sites and potencies in a functional H3 receptor model. Naunyn Schmiedebergs Arch Pharmacol 348:498-503 (1993). Read more (PubMed: 8114949) »
  • Garbarg M  et al. S-[2-(4-imidazolyl)ethyl]isothiourea, a highly specific and potent histamine H3 receptor agonist. J Pharmacol Exp Ther 263:304-10 (1992). Read more (PubMed: 1383495) »

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