Imiloxan hydrochloride, alpha2B adrenoceptor antagonist (ab141137)

Overview

  • Product name

    Imiloxan hydrochloride, alpha2B adrenoceptor antagonist
  • Description

    Highly selective α2B adrenoceptor antagonist
  • Biological description

    Highly selective α2B adrenoceptor antagonist (pKi = 7.26). Displays 55-fold higher affinity for α2B compared to α2A. Active in vivo.
  • Purity

    > 98%
  • CAS Number

    81167-22-8
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Villalón CM  et al. Pharmacological profile of the clonidine-induced inhibition of vasodepressor sensory outflow in pithed rats: correlation with alpha(2A/2C)-adrenoceptors. Br J Pharmacol 154:51-9 (2008). Read more (PubMed: 18297098) »
  • Takano Y  et al. The effect of intrathecally administered imiloxan and WB4101: possible role of alpha 2-adrenoceptor subtypes in the spinal cord. Eur J Pharmacol 219:465-8 (1992). Read more (PubMed: 1358645) »
  • Michel AD  et al. Assessment of imiloxan as a selective alpha 2B-adrenoceptor antagonist. Br J Pharmacol 99:560-4 (1990). Read more (PubMed: 1970500) »

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab141137.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
For licensing inquiries, please contact partnerships@abcam.com

Sign up