Overview

  • Product name

  • Description

    Rabbit polyclonal to IMPA1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, IHC-P, WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Recombinant fragment corresponding to Human IMPA1.
    Database link: P29218

  • Positive control

    • SKOV3, SW620, Jurkat, SHSY5Y, mouse liver, mouse kidney, mouse brain and rat thymus cell extracts. A549 cells.

Properties

Applications

Our Abpromise guarantee covers the use of ab202131 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use at an assay dependent concentration.
IHC-P 1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
WB 1/500 - 1/2000. Predicted molecular weight: 30 kDa.

Target

  • Function

    Responsible for the provision of inositol required for synthesis of phosphatidylinositol and polyphosphoinositides and has been implicated as the pharmacological target for lithium action in brain. Can use myo-inositol monophosphates, myo-inositol-1,3-diphosphate, myo-inositol-1,4-diphosphate, scyllo-inositol-phosphate, glucose-1-phosphate, glucose-6-phosphate, fructose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates.
  • Pathway

    Polyol metabolism; myo-inositol biosynthesis; myo-inositol from D-glucose 6-phosphate: step 2/2.
  • Sequence similarities

    Belongs to the inositol monophosphatase family.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • IMP 1 antibody
    • IMP antibody
    • IMPA 1 antibody
    • IMPA antibody
    • IMPA1 antibody
    • IMPA1_HUMAN antibody
    • IMPase 1 antibody
    • IMPase antibody
    • Inositol 1(or 4) monophosphatase antibody
    • Inositol monophosphatase 1 antibody
    • Inositol monophosphatase antibody
    • Inositol(myo) 1(or 4) monophosphatase 1 antibody
    • Inositol-1(or 4)-monophosphatase 1 antibody
    • Lithium sensitive myo inositol monophosphatase A1 antibody
    • Lithium-sensitive myo-inositol monophosphatase A1 antibody
    see all

Images

  • Immunofluorescence analysis of A549 cells labeling IMPA1 with ab202131. Counter-stained with DAPI for nuclear staining.

  • All lanes : Anti-IMPA1 antibody (ab202131) at 1/500 dilution

    Lane 1 : SKOV3 cell extract
    Lane 2 : SW620 cell extract
    Lane 3 : Jurkat cell extract
    Lane 4 : SHSY5Y cell extract
    Lane 5 : Mouse liver cell extract
    Lane 6 : Mouse kidney cell extract
    Lane 7 : Mouse brain cell extract
    Lane 8 : Rat thymus cell extract

    Developed using the ECL technique.

    Predicted band size: 30 kDa

References

ab202131 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab202131.
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