Key features and details
- Mouse polyclonal to IMPACT
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-IMPACT antibody
See all IMPACT primary antibodies
DescriptionMouse polyclonal to IMPACT
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Full length native protein (purified), corresponding to amino acids 1-320 of Human IMPACT
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.4
Constituent: 2.68% PBS
Concentration information loading...
PurityProtein G purified
Our Abpromise guarantee covers the use of ab72444 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use at an assay dependent dilution. Predicted molecular weight: 36 kDa.|
FunctionTranslational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis.
Tissue specificityWidely expressed. Expressed at high level in brain.
Sequence similaritiesBelongs to the IMPACT family.
Contains 1 RWD domain.
- Information by UniProt
- IMPACT antibody
- Impact homolog (mouse) antibody
- Impact homolog antibody
ab72444 has been referenced in 1 publication.
- Habibi D et al. High expression of IMPACT protein promotes resistance to indoleamine 2,3-dioxygenase-induced cell death. J Cell Physiol 225:196-205 (2010). WB ; Human . PubMed: 20648630