Product nameAnti-Importin 9/RANBP9 antibody - C-terminal
See all Importin 9/RANBP9 primary antibodies
DescriptionRabbit polyclonal to Importin 9/RANBP9 - C-terminal
ab198782 detects endogenous levels of total Importin 9/RANBP9 protein.
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Mouse, Human
Synthetic peptide corresponding to Human Importin 9/RANBP9 (C terminal). NP_060555.
Database link: Q96P70
- Human fetal brain and HeLa lysates; Human thyroid cancer tissue.
This product was previously labelled as Importin 9
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.3
Preservative: 0.05% Sodium azide
Constituents: 50% Glycerol, 49% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab198782 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/200.|
|WB||1/200 - 1/1000. Predicted molecular weight: 116 kDa.|
FunctionFunctions in nuclear protein import as nuclear transport receptor. Serves as receptor for nuclear localization signals (NLS) in cargo substrates. Is thought to mediate docking of the importin/substrate complex to the nuclear pore complex (NPC) through binding to nucleoporin and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to the importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus (By similarity). Mediates the nuclear import of H2B histone (By similarity), RPS7 and RPL18A. Prevents the cytoplasmic aggregation of RPS7 and RPL18A by shielding exposed basic domains. May also import H2A, H3, H4 histones (By similarity), RPL4 and RPL6.
Sequence similaritiesBelongs to the importin beta family.
Contains 1 importin N-terminal domain.
Cellular localizationCytoplasm. Nucleus.
- Information by UniProt
- Imp9 antibody
- Imp9a antibody
- Imp9b antibody
All lanes : Anti-Importin 9/RANBP9 antibody - C-terminal (ab198782) at 1/200 dilution
Lane 1 : Human fetal brain lysate
Lane 2 : HeLa cell lysate
Lysates/proteins at 40 µg per lane.
Predicted band size: 116 kDa
Exposure time: 30 seconds
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling Importin 9/RANBP9 with ab198782 at 1/40 dilution.
ab198782 has not yet been referenced specifically in any publications.