Key features and details
- Rabbit polyclonal to Influenza A Nonstructural Protein 1
- Suitable for: ELISA
- Reacts with: Influenza A
- Isotype: IgG
Product nameAnti-Influenza A Nonstructural Protein 1 antibody
DescriptionRabbit polyclonal to Influenza A Nonstructural Protein 1
SpecificitySpecific for the seasonal Influenza A Nonstructural Protein 1. Does not bind the corresponding Nonstructural Protein 1 from the swine flu Influenza A virus.
Tested applicationsSuitable for: ELISAmore details
Species reactivityReacts with: Influenza A
Synthetic peptide specific for the seasonal Influenza A H1N1 Nonstructural Protein 1 (ABP49398).
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab91642 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||Use at an assay dependent dilution.|
RelevanceInfluenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. The virus has one of sixteen possible hemagglutinin (HA) surface proteins and one of nine possible neuraminidase (NA) surface proteins. In early 2009, a novel H1N1 swine-origin influenza (S-OIV) A virus was identified in specimens obtained from patients in Mexico and the United States. The genetic make-up of this swine flu virus is unlike any other: it is an H1N1 strain that combines a triple assortment first identified in 1998 including human, swine, and avian influenza with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin. One of the less studied proteins encoded by, but not incorporated in, the influenza virus is the nonstructural protein (NS) 1. NS1 counters cellular antiviral activities and acts as a virulence factor. It can bind to double-stranded RNA and sequester it from 2’-5’ OAS, preventing the activation of the RNAse L, which normally acts to degrade RNA and prevent virus replication. NS1 also binds to and inhibits the antiviral protein kinase PKR.
Cellular localizationhost cell cytoplasm and nucleus
- SwissProt: P03496 Influenza A
- Nonstructural protein 1 antibody
- NS1 antibody
- NS1A antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab91642 has not yet been referenced specifically in any publications.