Anti-Influenza A Nonstructural Protein 1 antibody (ab91642)
Key features and details
- Rabbit polyclonal to Influenza A Nonstructural Protein 1
- Suitable for: ELISA
- Reacts with: Influenza A
- Isotype: IgG
Overview
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Product name
Anti-Influenza A Nonstructural Protein 1 antibody
See all Influenza A Nonstructural Protein 1 primary antibodies -
Description
Rabbit polyclonal to Influenza A Nonstructural Protein 1 -
Host species
Rabbit -
Specificity
Specific for the seasonal Influenza A Nonstructural Protein 1. Does not bind the corresponding Nonstructural Protein 1 from the swine flu Influenza A virus. -
Tested applications
Suitable for: ELISAmore details -
Species reactivity
Reacts with: Influenza A -
Immunogen
Synthetic peptide specific for the seasonal Influenza A H1N1 Nonstructural Protein 1 (ABP49398).
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.2
Preservative: 0.02% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab91642 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use at an assay dependent dilution.
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Notes |
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ELISA
Use at an assay dependent dilution. |
Target
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Relevance
Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. The virus has one of sixteen possible hemagglutinin (HA) surface proteins and one of nine possible neuraminidase (NA) surface proteins. In early 2009, a novel H1N1 swine-origin influenza (S-OIV) A virus was identified in specimens obtained from patients in Mexico and the United States. The genetic make-up of this swine flu virus is unlike any other: it is an H1N1 strain that combines a triple assortment first identified in 1998 including human, swine, and avian influenza with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin. One of the less studied proteins encoded by, but not incorporated in, the influenza virus is the nonstructural protein (NS) 1. NS1 counters cellular antiviral activities and acts as a virulence factor. It can bind to double-stranded RNA and sequester it from 2’-5’ OAS, preventing the activation of the RNAse L, which normally acts to degrade RNA and prevent virus replication. NS1 also binds to and inhibits the antiviral protein kinase PKR. -
Cellular localization
host cell cytoplasm and nucleus -
Database links
- SwissProt: P03496 Influenza A
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Alternative names
- Nonstructural protein 1 antibody
- NS1 antibody
- NS1A antibody
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab91642 has not yet been referenced specifically in any publications.