Overview

  • Product name

    Anti-Influenza A Virus Hemagglutinin H5 antibody [15A6]
  • Description

    Mouse monoclonal [15A6] to Influenza A Virus Hemagglutinin H5
  • Host species

    Mouse
  • Specificity

    Detects haemagglutinin H5 from the Influenza A virus H5N1.
  • Tested applications

    Suitable for: ELISAmore details
  • Species reactivity

    Reacts with: Influenza A
  • Immunogen

    Purified avian influenza virus type A (H5N1)

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • Storage buffer

    Preservative: 0.09% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • Purity

    Protein G purified
  • Clonality

    Monoclonal
  • Clone number

    15A6
  • Myeloma

    Sp2/0
  • Isotype

    IgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab59166 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent dilution.

Target

  • Relevance

    Influenza A belongs to the Orthomyxoviridae family, and is a negative sense single-stranded RNA virus which results in respiratory disease. Haemagglutinin is an antigenic glycoprotein which allows viral attachment and entry into the cell. Sixteen subtypes of haemagglutinin (H1-H16) have been described, of which H1, H2 and H3 infect humans. H5 and H7 normally result in avian disease, with some highly pathogenic H5N1 strains causing 100% mortality in poultry. H5N1 has in some cases mutated to infect humans, with 60% mortality. Haemagglutinin is one of the most medically relevant antigens on influenza as it is a target for antiviral drugs and antibodies.
  • Database links

    • Alternative names

      • H5HA antibody
      • Hemagglutinin 5 antibody

    References

    ab59166 has not yet been referenced specifically in any publications.

    Customer reviews and Q&As

    Answer

    Thank you for your enquiry.

    I have contacted the originators of these antibodies, who have kindly provided the following testing results from various Influenza A virus strains with these antibodies:

    ab59166 Influenza A Virus Hemagglutinin H5 antibody [15A6]

    According to the originator, this clone is reactive to strains which express H5 (ie H5N1, H5N2, H5N9). It is not reactive to any other strains that do not express the H5 antigen.

    ab73453 Influenza A Virus Hemagglutinin H5 antibody [B253M]

    This antibody tested negative with recombinant H1, H3, H7, H9

    ab73454 Influenza A Virus Hemagglutinin H5 antibody [B254M]

    Has been tested on the following strains:

    H5: A/Vietnam/1203/04 (positive)
    H5: A/HK/156/97 (positive)
    H5N2 (Venice) (positive)
    H5N9 (USA (positive)
    H5/Clade 2 isolate Far East (negative)
    H5: A/HK/213/03 (negative)
    H1: A/New Caledonia/20/99 (negative)
    H1: A/duck/Alberta/35/78 (negative)
    H1: A/sw/Iowa/30 (negative)
    H1: A/USSR90/77 (negative)
    H3: A/Wyoming/03/2003 (H3) (negative)
    H3: A/Equine 2 /Miami/63 (negative)
    H3: A/duck/Ukraine/63 (negative)
    H7: FPV (negative)
    H8: A/turkey/Ontario/61/81/68 (negative)
    H9: A/HK/107/99 (H9) (negative)
    H9: A/turkey/Wiconsin/66 (negative)
    H10: A/chicken/Germany/N/49 (negative)
    H11: A/duck/England/56 (negative)
    H12: A/duck/Alberta /68/76 (negative)
    H13: A/gull/Turkmenia/13/77(negative)

    ab73456 Influenza A Virus Hemagglutinin H5 antibody [B256M]

    Has been tested on the following strains:

    H5: A/Vietnam/1203/04 (positive)
    H5: A/HK/156/97 (positive)
    H5N2 (Venice) (positive)
    H5N9 (USA (positive)
    H5/Clade 2 isolate Far East (negative)
    H5: A/HK/213/03 (negative)
    H1: A/New Caledonia/20/99 (negative)
    H1: A/duck/Alberta/35/78 (negative)
    H1: A/sw/Iowa/30 (negative)
    H1: A/USSR90/77 (negative)
    H3: A/Wyoming/03/2003 (H3) (negative)
    H3: A/Equine 2 /Miami/63 (negative)
    H3: A/duck/Ukraine/63 (negative)
    H7: FPV (negative)
    H8: A/turkey/Ontario/61/81/68 (negative)
    H9: A/HK/107/99 (H9) (negative)
    H9: A/turkey/Wiconsin/66 (negative)
    H10: A/chicken/Germany/N/49 (negative)
    H11: A/duck/England/56 (negative)
    H12: A/duck/Alberta /68/76 (negative)
    H13: A/gull/Turkmenia/13/77(negative)

    ab82455 H5 (H5N1) antibody [8D2]

    This antibody is specific to haemagglutinin H5 of influenza A. It has been tested for example with following strains:

    A/Chicken/Indonesia/Wates1/2005 (H5N1)Negative
    A/Chicken/Indonesia/Wates130/2005 (H5N1) Negative
    A/Duck/Vietnam/942B/2004 (H5N1)Positive
    A/Vietnam/1194/2004 (H5N1)Positive
    A/Vietnam/1203/2004 (H5N1)Positive
    A/Vietnam/1204/2004 (H5N1)Positive
    A/Hong Kong/213/03 (H5N1)Positive
    A/Hong Kong/156/97 (H5N1)Positive
    A/New Caledonia/20/99 (H1N1)Negative
    A/Wyoming/03/2003 (H3N2)Negative
    A/Netherlands/219/03 (H7N7)
    A/Hong Kong/1073/99 (H9N2)Negative

    It has been tested also with recombinant heamagglutinins H1-H4 and H6-H15 and results were negative with them.

    I hope this will be helpful to you. If you have any further questions, please do not hesitate to contact us.

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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