Key features and details
- Rabbit polyclonal to Influenza A Virus Nucleoprotein
- Suitable for: ELISA
- Reacts with: Influenza A
- Isotype: IgG
Product nameAnti-Influenza A Virus Nucleoprotein antibody
See all Influenza A Virus Nucleoprotein primary antibodies
DescriptionRabbit polyclonal to Influenza A Virus Nucleoprotein
Specificityab91648 is specific for the seasonal Influenza A Virus Nucleoprotein and will not recognize the corresponding Nucleoprotein sequence from the swine origin H1N1 influenza (A/California/14/2009 (H1N1)).
Tested applicationsSuitable for: ELISAmore details
Species reactivityReacts with: Influenza A
A synthetic peptide from the Seasonal Influenza A Virus Nucleoprotein (H1N1) (Genbank accession AFK14863).
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Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.2
Preservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Purification notesAffinity chromatography purified via peptide column.
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab91648 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
RelevanceThe nucleoprotein (NP) of Influenza virus encapsulates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. "NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56" (Portela et al 2002).
Cellular localizationHost cell nucleus
- Common flu NP antibody
- Influenza A virus NP antibody
- NP antibody
ab91648, at a concentration of 1 µg/ml, detects seasonal Influenza A Virus Nucleoprotein by Elisa. It does not recognize the corresponding Nucleoprotein sequence from the swine origin H1N1 influenza (A/California/14/2009 (H1N1)). The blocking and corresponding peptides were used at 60, 10, 2 and 0 ng/ml.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab91648 has been referenced in 1 publication.
- Motawea HKB et al. Human Placenta Expresses a2-Adrenergic Receptors and May Be Implicated in Pathogenesis of Preeclampsia and Fetal Growth Restriction. Am J Pathol 188:2774-2785 (2018). PubMed: 30273604