Overview

  • Product name

    Anti-Influenza A Virus Nucleoprotein antibody
    See all Influenza A Virus Nucleoprotein primary antibodies
  • Description

    Rabbit polyclonal to Influenza A Virus Nucleoprotein
  • Host species

    Rabbit
  • Specificity

    ab91648 is specific for the seasonal Influenza A Virus Nucleoprotein and will not recognize the corresponding Nucleoprotein sequence from the swine origin H1N1 influenza (A/California/14/2009 (H1N1)).
  • Tested applications

    Suitable for: ELISAmore details
  • Species reactivity

    Reacts with: Influenza A
  • Immunogen

    A synthetic peptide from the Seasonal Influenza A Virus Nucleoprotein (H1N1) (Genbank accession AFK14863).

Properties

Applications

Our Abpromise guarantee covers the use of ab91648 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA
  • Application notes
    ELISA: Use at a concentration of 1 µg/ml.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • Target

    • Relevance

      The nucleoprotein (NP) of Influenza virus encapsulates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. "NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56" (Portela et al 2002).
    • Cellular localization

      Host cell nucleus
    • Database links

      • Alternative names

        • Common flu NP antibody
        • Influenza A virus NP antibody
        • NP antibody
        • Nucleocapsid protein antibody
        • Nucleoprotein antibody
        • Protein N antibody
        • Seasonal Influenza A (H1N1) Nucleocapsid Protein antibody
        see all

      Images

      • ab91648, at a concentration of 1 µg/ml, detects seasonal Influenza A Virus Nucleoprotein by Elisa. It does not recognize the corresponding Nucleoprotein sequence from the swine origin H1N1 influenza (A/California/14/2009 (H1N1)). The blocking and corresponding peptides were used at 60, 10, 2 and 0 ng/ml.

      References

      This product has been referenced in:

      • Motawea HKB  et al. Human Placenta Expresses a2-Adrenergic Receptors and May Be Implicated in Pathogenesis of Preeclampsia and Fetal Growth Restriction. Am J Pathol 188:2774-2785 (2018). Read more (PubMed: 30273604) »
      See 1 Publication for this product

      Customer reviews and Q&As

      Answer

      The sequence homology between the immunogen for ab91648 and your target is around 62.5%. Based on this, ab91648 probably will not cross-react with your target.

      Read More

      Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
      For licensing inquiries, please contact partnerships@abcam.com

      Sign up