Overview

  • Product name
    Anti-Influenza A Virus Nucleoprotein antibody [C43] (HRP)
    See all Influenza A Virus Nucleoprotein primary antibodies
  • Description
    Mouse monoclonal [C43] to Influenza A Virus Nucleoprotein (HRP)
  • Host species
    Mouse
  • Conjugation
    HRP
  • Tested applications
    Suitable for: IHC, ELISA, WB, ICCmore details
  • Species reactivity
    Reacts with: Influenza A
  • Immunogen

    Tissue, cells or virus corresponding to Influenza A Virus Nucleoprotein.

Properties

Applications

Our Abpromise guarantee covers the use of ab176837 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC 1/200.
ELISA Use at an assay dependent concentration.
WB 1/300 - 1/1000. Predicted molecular weight: 56 kDa.
ICC 1/200.

Target

  • Relevance
    The nucleoprotein (NP) of Influenza virus encapsulates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. "NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56" (Portela et al 2002).
  • Cellular localization
    Host cell nucleus
  • Database links
    • Alternative names
      • Common flu NP antibody
      • Influenza A virus NP antibody
      • NP antibody
      • Nucleocapsid protein antibody
      • Nucleoprotein antibody
      • Protein N antibody
      • Seasonal Influenza A (H1N1) Nucleocapsid Protein antibody
      see all

    References

    ab176837 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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