Overview

  • Product name

    Anti-Influenza A Virus Nucleoprotein antibody [F8]
    See all Influenza A Virus Nucleoprotein primary antibodies
  • Description

    Mouse monoclonal [F8] to Influenza A Virus Nucleoprotein
  • Host species

    Mouse
  • Specificity

    ab67428 recognises influenza virus type A nucleoprotein. The antibody binds to a conserved epitope on the nucleoprotein that is common for influenza A (H1N1), (H3N3) and other influenza A viruses. It does not cross react with influenza virus type B.
  • Tested applications

    Suitable for: ELISA, IHC-Frmore details
  • Species reactivity

    Reacts with: Influenza A
  • Immunogen

    Purified influenza virus type A (H1N1)

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Storage buffer

    Preservative: 0.09% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • Purity

    Protein G purified
  • Clonality

    Monoclonal
  • Clone number

    F8
  • Myeloma

    Sp2/0
  • Isotype

    IgG2a
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab67428 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ELISA Use at an assay dependent concentration.
IHC-Fr Use at an assay dependent concentration.

Target

  • Relevance

    The nucleoprotein (NP) of Influenza virus encapsulates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. "NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56" (Portela et al 2002).
  • Cellular localization

    Host cell nucleus
  • Database links

    • Alternative names

      • Common flu NP antibody
      • Influenza A virus NP antibody
      • NP antibody
      • Nucleocapsid protein antibody
      • Nucleoprotein antibody
      • Protein N antibody
      • Seasonal Influenza A (H1N1) Nucleocapsid Protein antibody
      see all

    References

    This product has been referenced in:

    • Leirs K  et al. Bioassay Development for Ultrasensitive Detection of Influenza A Nucleoprotein Using Digital ELISA. Anal Chem 88:8450-8 (2016). Read more (PubMed: 27487722) »
    See 1 Publication for this product

    Customer reviews and Q&As

    Answer

    Thank you for contacting us. The antibodies have different clone number, concentration is different, purity is different, storage buffer percentage is different, and these are tested in different applications. Although these products are against same target but they are different in above mentioned properties. I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.  

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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