Anti-Influenza A Virus Nucleoprotein antibody [F8] (ab67428)
Key features and details
- Mouse monoclonal [F8] to Influenza A Virus Nucleoprotein
- Suitable for: ELISA, IHC-Fr
- Reacts with: Influenza A
- Isotype: IgG2a
Overview
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Product name
Anti-Influenza A Virus Nucleoprotein antibody [F8]
See all Influenza A Virus Nucleoprotein primary antibodies -
Description
Mouse monoclonal [F8] to Influenza A Virus Nucleoprotein -
Host species
Mouse -
Specificity
ab67428 recognises influenza virus type A nucleoprotein. The antibody binds to a conserved epitope on the nucleoprotein that is common for influenza A (H1N1), (H3N3) and other influenza A viruses. It does not cross react with influenza virus type B. -
Tested applications
Suitable for: ELISA, IHC-Frmore details -
Species reactivity
Reacts with: Influenza A -
Immunogen
Tissue, cells or virus corresponding to Influenza A Virus Nucleoprotein. Purified influenza virus type A (H1N1)
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.40
Preservative: 0.09% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
F8 -
Myeloma
Sp2/0 -
Isotype
IgG2a -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab67428 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use at an assay dependent concentration.
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IHC-Fr |
Use at an assay dependent concentration.
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Notes |
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ELISA
Use at an assay dependent concentration. |
IHC-Fr
Use at an assay dependent concentration. |
Target
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Relevance
The nucleoprotein (NP) of Influenza virus encapsulates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. "NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56" (Portela et al 2002). -
Cellular localization
Host cell nucleus -
Database links
- Entrez Gene: 956531 Influenza A
- SwissProt: P03466 Influenza A
- SwissProt: P69291 Influenza A
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Alternative names
- Common flu NP antibody
- Influenza A virus NP antibody
- NP antibody
see all
Datasheets and documents
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Datasheet download
References (1)
ab67428 has been referenced in 1 publication.
- Leirs K et al. Bioassay Development for Ultrasensitive Detection of Influenza A Nucleoprotein Using Digital ELISA. Anal Chem 88:8450-8 (2016). PubMed: 27487722