Product nameAnti-ING1 antibody (HRP)
See all ING1 primary antibodies
DescriptionRabbit polyclonal to ING1 (HRP)
SpecificityThis antibody recognize p33 ING1, doesn't crossreact with other ING family.
Tested applicationsSuitable for: ELISA, WBmore details
Species reactivityReacts with: Mouse, Human
Synthetic peptide (Mouse) conjugated to KLH - mouse p33 ING1 N-terminal peptide -KLH conjugates
The antibody was conjugated to HRP with reductive amination with 2/1 molar ratio of HRP/antibody.
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferPreservative: 0.1% Sodium azide
Constituent: Tris buffered saline
Concentration information loading...
PurityImmunogen affinity purified
Purification notesThis antibody was purified with the p33 ING c-terminal peptide on Agarose
- TMB ELISA Substrate (Highest Sensitivity) (ab171522)
- TMB ELISA Substrate (High Sensitivity) (ab171523)
- TMB ELISA Substrate (Fast Kinetic Rate) (ab171524)
- TMB ELISA Substrate (Slow Kinetic Rate) (ab171525)
- TMB ELISA Substrate (Slower Kinetic Rate) (ab171526)
- TMB ELISA Substrate (Slowest Kinetic Rate) (ab171527)
- 450 nm Stop Solution for TMB Substrate (ab171529)
- 650 nm Stop Solution for TMB Substrate (ab171531)
- Immunoassay Blocking Buffer (ab171534)
- Immunoassay Blocking (BSA Free) (ab171535)
Our Abpromise guarantee covers the use of ab28556 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ELISA||Use a concentration of 0.25 µg/ml.|
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 47 kDa.|
FunctionCooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor gene.
Tissue specificityIsoform 2 was expressed in all normal tissues and cells examined, as well as in all breast cancer and melanoma cell lines examined. Isoform 3 was expressed in testis, liver, and kidney, weakly expressed in colon and brain and not expressed in breast and cultured melanocytes. Isoform 4 was highly expressed in testis and weakly expressed in brain, but not expressed in breast, colon, kidney, melanocytes, breast cancer or melanoma cell lines.
Involvement in diseaseDefects in ING1 are a cause of head and neck squamous cell carcinomas (HNSCC) [MIM:275355]; also known as squamous cell carcinoma of the head and neck.
Sequence similaritiesBelongs to the ING family.
Contains 1 PHD-type zinc finger.
- Information by UniProt
- 2610028J21Rik antibody
- AA407184 antibody
- AI875420 antibody
ab28556 has not yet been referenced specifically in any publications.