Overview

  • Product name

  • Description

    Rabbit polyclonal to INHBC
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-P, WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Fusion protein corresponding to Human INHBC (internal sequence). The identity of the protein fusion partner is GST.
    Database link: P55103

  • Positive control

    • 293T, HepG2, HeLa and A549 cell lysates; Human thyroid cancer tissue.
  • General notes

     This product was previously labelled as Inhibin beta C chain

     

Properties

Applications

Our Abpromise guarantee covers the use of ab197692 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/200.
WB 1/500 - 1/2000. Predicted molecular weight: 38 kDa.

Target

  • Function

    Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
  • Tissue specificity

    Expressed in benign prostatic hyperplasia.
  • Sequence similarities

    Belongs to the TGF-beta family.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • Activin beta C chain antibody
    • Activin beta-C chain antibody
    • IHBC antibody
    • Inhbc antibody
    • INHBC_HUMAN antibody
    • Inhibin beta C chain antibody
    • Inhibin, beta C antibody
    see all

Images

  • All lanes : Anti-INHBC antibody (ab197692) at 1/550 dilution

    Lane 1 : 293T cell lysate
    Lane 2 : HepG2 cell lysate
    Lane 3 : HeLa cell lysate
    Lane 4 : A549 cell lysate

    Lysates/proteins at 40 µg per lane.

    Predicted band size: 38 kDa


    Exposure time: 1 minute


    10% SDS-PAGE

  • Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue labeling INHBC with ab197692 at 1/50 dilution.

References

ab197692 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab197692.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up