Anti-Inhibin beta A antibody (ab56057)
Key features and details
- Rabbit polyclonal to Inhibin beta A
- Suitable for: ELISA, WB
- Reacts with: Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-Inhibin beta A antibody
See all Inhibin beta A primary antibodies -
Description
Rabbit polyclonal to Inhibin beta A -
Host species
Rabbit -
Tested applications
Suitable for: ELISA, WBmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Rat -
Immunogen
Synthetic peptide corresponding to Human Inhibin beta A (N terminal). A synthetic peptide corresponding to N-terminal residues of human INHBA (Inhibin beta A chain precursor)
Database link: P08476 -
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), PBS -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab56057 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use at an assay dependent concentration.
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WB | (1) |
Use at an assay dependent concentration.
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Notes |
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ELISA
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
Target
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Function
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. -
Sequence similarities
Belongs to the TGF-beta family. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 3624 Human
- Entrez Gene: 16323 Mouse
- Entrez Gene: 29200 Rat
- Omim: 147290 Human
- SwissProt: P08476 Human
- SwissProt: Q04998 Mouse
- SwissProt: P18331 Rat
- Unigene: 583348 Human
see all -
Alternative names
- Activin beta-A chain antibody
- EDF antibody
- Erythroid differentiation factor antibody
see all
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (6)
ab56057 has been referenced in 6 publications.
- Webb BM et al. TGF-β/activin signaling promotes CDK7 inhibitor resistance in triple-negative breast cancer cells through upregulation of multidrug transporters. J Biol Chem 297:101162 (2021). PubMed: 34481843
- Wei S et al. Differences in the Structure and Protein Expression of Femoral Nerve Branches in Rats. Front Neuroanat 14:16 (2020). PubMed: 32322192
- Peng S et al. INHBA knockdown inhibits proliferation and invasion of nasopharyngeal carcinoma SUNE1 cells in vitro. Int J Clin Exp Pathol 13:854-868 (2020). PubMed: 32509056
- Lyu S et al. INHBA upregulation correlates with poorer prognosis in patients with esophageal squamous cell carcinoma. Cancer Manag Res 10:1585-1596 (2018). PubMed: 29950896
- Nagaraja AS et al. Adrenergic-mediated increases in INHBA drive CAF phenotype and collagens. JCI Insight 2:N/A (2017). PubMed: 28814667
- Locci M et al. Activin A programs the differentiation of human TFH cells. Nat Immunol 17:976-84 (2016). PubMed: 27376469