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Rabbit polyclonal to Inhibin beta A
Synthetic peptide, corresponding to a sequence within amino acids 362-423 (SGSSLSFHST VINHYRMRGH SPFANLKSCC VPTKLRPMSM LYYDDGQNII KKDIQNMIVE EC) of Human Inhibin beta A (NP_002183).
H1299, HeLa S3 and HepG2 whole cell lysates; HeLa cells; 293T, A431, MOLT4 and Raji cell lines.
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Preservative: 0.01% Thimerosal (merthiolate) Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol
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Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/3000. Predicted molecular weight: 47 kDa.
1/100 - 1/200.
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
Belongs to the TGF-beta family.
Information by UniProt
Activin beta-A chain antibody
Erythroid differentiation factor antibody
Western blot - Anti-Inhibin beta A antibody (ab97705)
All lanes : Anti-Inhibin beta A antibody (ab97705) at 1/1000 dilution Lane 1 : H1299 whole cell lysate Lane 2 : HeLa S3 whole cell lysate Lane 3 : HepG2 whole cell lysate Lysates/proteins at 30 µg per lane. Predicted band size: 47 kDa 10% SDS-PAGE.
Immunocytochemistry/ Immunofluorescence - Anti-Inhibin beta A antibody (ab97705)
ab97705, at 1/200 dilution, staining Inhibin beta A in paraformaldehyde-fixed HeLa cells by Immunofluorescence. Lower image is merged with DNA probe.
This product has been referenced in:
et al. IL-1beta stimulates activin betaA mRNA expression in human skin fibroblasts through the MAPK pathways, the nuclear factor-kappaB pathway, and prostaglandin E2. Endocrinology 152:3779-90 (2011).
Read more (PubMed: 21828177) »
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"