Recombinant
RabMAb

Recombinant Anti-Inhibin beta B antibody [EPR2788(2)] (ab128944)

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Overview

  • Product name

    Anti-Inhibin beta B antibody [EPR2788(2)]
    See all Inhibin beta B primary antibodies

  • Description

    Rabbit monoclonal [EPR2788(2)] to Inhibin beta B

  • Host species

    Rabbit

  • Tested applications

    Suitable for: WBmore details
    Unsuitable for: IHC-P or IP

  • Species reactivity

    Reacts with: Mouse, Rat, Human

  • Immunogen

    Synthetic peptide corresponding to Human Inhibin beta B aa 350 to the C-terminus.
    Database link: P09529
    (Peptide available as ab174743)

  • Positive control

    • Mouse brain and Rat brain lysates; Human Inhibin beta B recombinant protein (mature form: 17 kDa)

  • General notes

     

     

    This product is a recombinant monoclonal antibody, which offers several advantages including:

    • - High batch-to-batch consistency and reproducibility
    • - Improved sensitivity and specificity
    • - Long-term security of supply
    • - Animal-free production
    For more information see here.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.

Properties

Applications

Our Abpromise guarantee covers the use of ab128944 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000 - 1/10000. Detects a band of approximately 52, 17 kDa (predicted molecular weight: 45 kDa).
  • Application notes
    Is unsuitable for IHC-P or IP.

    • Target

    • Function

      Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.

    • Sequence similarities

      Belongs to the TGF-beta family.

    • Cellular localization

      Secreted.
    • Information by UniProt

    • Database links

      see all

    • Alternative names

      • Activin beta B chain antibody
      • Activin beta-B chain antibody
      • INHBB antibody
      • INHBB_HUMAN antibody
      • Inhibin beta 2 antibody
      • Inhibin beta B chain antibody
      • Inhibin beta B subunit antibody
      see all

    Images

    • Western blot - Anti-Inhibin beta B antibody [EPR2788(2)] (ab128944)
      Western blot - Anti-Inhibin beta B antibody [EPR2788(2)] (ab128944)
      All lanes : Anti-Inhibin beta B antibody [EPR2788(2)] (ab128944) at 1/1000 dilution

      Lane 1 : Mouse brain lysate
      Lane 2 : Rat brain lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      All lanes : HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 45 kDa
      Observed band size: 52 kDa
      why is the actual band size different from the predicted?

    • Western blot - Anti-Inhibin beta B antibody [EPR2788(2)] (ab128944)
      Western blot - Anti-Inhibin beta B antibody [EPR2788(2)] (ab128944)
      Anti-Inhibin beta B antibody [EPR2788(2)] (ab128944) at 1/1000 dilution + Human Inhibin beta B recombinant protein (mature form:
      17 kDa) (10 ng)

      Secondary
      HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size: 45 kDa

    • Other - Anti-Inhibin beta B antibody [EPR2788(2)] (ab128944)
      Other - Anti-Inhibin beta B antibody [EPR2788(2)] (ab128944)
      Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    References

    ab128944 has not yet been referenced specifically in any publications.

    Publishing research using ab128944? Please let us know so that we can cite the reference in this datasheet.

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