Recombinant
RabMAb

Recombinant Anti-Inhibin beta B antibody [EPR2788(2)] - BSA and Azide free (ab226845)

Overview

  • Product name

    Anti-Inhibin beta B antibody [EPR2788(2)] - BSA and Azide free
    See all Inhibin beta B primary antibodies
  • Description

    Rabbit monoclonal [EPR2788(2)] to Inhibin beta B - BSA and Azide free
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Mouse, Rat, Human
  • Immunogen

    Synthetic peptide within Human Inhibin beta B aa 350 to the C-terminus. The exact sequence is proprietary.
    Database link: P09529
    (Peptide available as ab174743)

  • Positive control

    • WB: Human Inhibin beta B recombinant protein (mature form: 17 kDa)
  • General notes

    Ab226845 is the carrier-free version of ab128944. This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.

     

    Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.

    Use our conjugation kits  for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.

    ab226845 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.

    Maxpar® is a trademark of Fluidigm Canada Inc.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.

    This product is a recombinant rabbit monoclonal antibody.

Properties

Applications

Our Abpromise guarantee covers the use of ab226845 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Detects a band of approximately 52, 17 kDa (predicted molecular weight: 45 kDa).

Target

  • Function

    Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
  • Sequence similarities

    Belongs to the TGF-beta family.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • Activin beta B chain antibody
    • Activin beta-B chain antibody
    • INHBB antibody
    • INHBB_HUMAN antibody
    • Inhibin beta 2 antibody
    • Inhibin beta B chain antibody
    • Inhibin beta B subunit antibody
    see all

Images

  • Equilibrium disassociation constant (KD)
    Learn more about KD

    Click here to learn more about KD

    This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA, glycerol, and sodium azide (ab128944).

  • Anti-Inhibin beta B antibody [EPR2788(2)] (ab128944) at 1/1000 dilution + Human Inhibin beta B recombinant protein (mature form: 17 kDa) (10 ng)

    Secondary
    Secondary: HRP labelled goat anti-rabbit at 1/2000 dilution

    Predicted band size: 45 kDa



    This data was developed using the same antibody clone in a different buffer formulation containing PBS, BSA, glycerol, and sodium azide (ab128944).

References

ab226845 has not yet been referenced specifically in any publications.

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