Anti-iNOS (phospho Y151) antibody (ab182640)
Key features and details
- Rabbit polyclonal to iNOS (phospho Y151)
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
Overview
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Product name
Anti-iNOS (phospho Y151) antibody
See all iNOS primary antibodies -
Description
Rabbit polyclonal to iNOS (phospho Y151) -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Rat
Predicted to work with: Mouse -
Immunogen
Synthetic peptide corresponding to Human iNOS (phospho Y151) conjugated to Keyhole Limpet Haemocyanin (KLH). (Q-Y-Y(p)-G-S) (NP_000616.3).
Database link: P35228 -
Positive control
- Rat kidney lysate.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 49% PBS, 0.88% Sodium chloride
Note: PBS without Mg2+ and Ca2+2+. -
Concentration information loading...
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Purity
Immunogen affinity purified -
Purification notes
ab182640 was purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide. -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab182640 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/500 - 1/1000. Predicted molecular weight: 131 kDa.
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Notes |
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WB
1/500 - 1/1000. Predicted molecular weight: 131 kDa. |
Target
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Function
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2. -
Tissue specificity
Expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Not expressed in the platelets. -
Sequence similarities
Belongs to the NOS family.
Contains 1 FAD-binding FR-type domain.
Contains 1 flavodoxin-like domain. - Information by UniProt
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Database links
- Entrez Gene: 18126 Mouse
- Entrez Gene: 24599 Rat
- SwissProt: P29477 Mouse
- SwissProt: Q06518 Rat
- Unigene: 2893 Mouse
- Unigene: 10400 Rat
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Alternative names
- HEP-NOS antibody
- Hepatocyte NOS antibody
- HEPNOS antibody
see all
Images
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab182640 has been referenced in 1 publication.
- Hitzerd E et al. Placental effects and transfer of sildenafil in healthy and preeclamptic conditions. EBioMedicine 45:447-455 (2019). PubMed: 31204276