Key features and details
- Rabbit polyclonal to Integrin alpha 2
- Suitable for: WB
- Reacts with: Mouse, Pig
- Isotype: IgG
Product nameAnti-Integrin alpha 2 antibody
See all Integrin alpha 2 primary antibodies
DescriptionRabbit polyclonal to Integrin alpha 2
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Mouse, Pig
Predicted to work with: Human
Recombinant fragment corresponding to Human Integrin alpha 2 aa 74-277. N-terminal His-tag and S-tag. Expressed in E.coli.
MHHHHHHSSGLVPRGSGMKETAAAKFERQHMDSPDLGTDDDDKAMADIGS EFENRMGDVYKCPVDLSTATCEKLNLQTSTSIPNVTEMKTNMSLGLILTR NMGTGGFLTCGPLWAQQCGNQYYTTGVCSDISPDFQLSASFSPATQPCPS LIDVVVVCDESNSIYPWDAVKNFLEKFVQGLDIGPTKTQVGLIQYANNPR VVFNLNTYKTKEEMIVATSQTSQYGGDLTNTFGAIQYARKYAYSAASGGR RSATKV
Database link: P17301
- WB: Porcine and mouse intestine tissue; Recombinant human integrin alpha 2 protein.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Purification notesAntigen-specific affinity chromatography followed by Protein A affinity chromatography.
Our Abpromise guarantee covers the use of ab231597 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 - 5 µg/ml.|
FunctionIntegrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
Sequence similaritiesBelongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain.
DomainThe integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
- Information by UniProt
- BR antibody
- CD 49b antibody
- CD49 antigen like family member B antibody
All lanes : Anti-Integrin alpha 2 antibody (ab231597) at 3 µg/ml
Lane 1 : Porcine intestine tissue lysate
Lane 2 : Mouse intestine tissue lysate
All lanes : HRP-Linked Guinea pig Anti-rabbit at 1/2000 dilution
Anti-Integrin alpha 2 antibody (ab231597) at 3 µg/ml + Recombinant human integrin alpha 2 protein.
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab231597 has not yet been referenced specifically in any publications.