Description

  • Product name

    Integrin alpha 3 peptide
  • Animal free

    No
  • Nature

    Synthetic

Associated products

Specifications

Our Abpromise guarantee covers the use of ab209428 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Integrin alpha 3 antibody (ab131055)

  • Form

    Liquid
  • Additional notes

    This is the blocking peptide for ab131055.

  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C.

General Info

  • Alternative names

    • AA407068
    • Antigen identified by monoclonal antibody J143
    • CD49 antigen like family member C
    • CD49 antigen-like family member C
    • CD49c
    • CD49c antigen
    • FLJ34631
    • FLJ34704
    • FRP 2
    • FRP-2
    • FRP2
    • Galactoprotein B3
    • GAP B3
    • GAPB3
    • Integrin alpha 3
    • Integrin alpha-3 light chain
    • Integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
    • ITA3_HUMAN
    • ITGA 3
    • Itga3
    • MSK18
    • VCA 2
    • VCA2
    • Very late activation protein 3 receptor alpha 3 subunit
    • VL3A
    • VLA 3 alpha chain
    • VLA 3 subunit alpha
    • VLA-3 subunit alpha
    • VLA3a
    see all
  • Function

    Integrin alpha-3/beta-1 is a receptor for fibronectin, laminin, collagen, epiligrin, thrombospondin and CSPG4. Alpha-3/beta-1 may mediate with LGALS3 the stimulation by CSPG4 of endothelial cells migration.
  • Tissue specificity

    Isoform alpha-3A is widely expressed. Isoform alpha-3B is expressed in brain and heart. In brain, both isoforms are exclusively expressed on vascular smooth muscle cells, whereas in heart isoform alpha-3A is strongly expressed on vascular smooth muscle cells, isoform alpha-3B is detected only on endothelial vein cells.
  • Sequence similarities

    Belongs to the integrin alpha chain family.
    Contains 7 FG-GAP repeats.
  • Post-translational
    modifications

    Isoform alpha-3A, but not isoform alpha-3B, is phosphorylated on serine residues. Phosphorylation increases after phorbol 12-myristate 13-acetate stimulation. Isoform alpha-3A is phosphorylated on Tyr-1051.
  • Cellular localization

    Membrane.
  • Information by UniProt

References

ab209428 has not yet been referenced specifically in any publications.

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