Key features and details
- Rat monoclonal [RM0059-2G18] to Integrin alpha 4+beta 7
- Suitable for: IP, Flow Cyt, IHC-P
- Reacts with: Mouse
- Isotype: IgG2a
Product nameAnti-Integrin alpha 4+beta 7 antibody [RM0059-2G18]
See all Integrin alpha 4+beta 7 primary antibodies
DescriptionRat monoclonal [RM0059-2G18] to Integrin alpha 4+beta 7
Tested applicationsSuitable for: IP, Flow Cyt, IHC-Pmore details
Species reactivityReacts with: Mouse
Cell lysates of mouse lymphocytes
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferConstituent: PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab73261 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IP||1/100 - 1/400.|
|Flow Cyt||1/50 - 1/200.|
|IHC-P||1/100 - 1/200.|
RelevanceIntegrin alpha 4 beta 7, also known as, the lymphocyte Peyer's patch adhesion molecule (LPAM1) is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha 4 beta 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria.
Cellular localizationMembrane; Single pass type I membrane protein.
- Antigen CD49D antibody
- CD49d antibody
- IA4 antibody
ab73261 has not yet been referenced specifically in any publications.