Biotin Anti-CD103 antibody [2E7] (ab25211)
Key features and details
- Biotin Armenian hamster monoclonal [2E7] to CD103
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: Biotin
- Isotype: IgG
Related conjugates and formulations
Overview
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Product name
Biotin Anti-CD103 antibody [2E7]
See all CD103 primary antibodies -
Description
Biotin Armenian hamster monoclonal [2E7] to CD103 -
Host species
Armenian hamster -
Conjugation
Biotin -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Tissue, cells or virus corresponding to CD103. C57BL/6J mouse intestinal intraepithelial lymphocytes (IEL)
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. Store In the Dark. -
Storage buffer
pH: 7.4
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
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Purity
Affinity purified -
Clonality
Monoclonal -
Clone number
2E7 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab25211 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
Flow Cyt |
Notes |
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IHC-Fr: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.
In vivo activation: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
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Function
Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. -
Tissue specificity
Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells. -
Sequence similarities
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain. -
Domain
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. -
Cellular localization
Membrane. - Information by UniProt
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Database links
- Entrez Gene: 16407 Mouse
- SwissProt: Q60677 Mouse
- Unigene: 96 Mouse
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Alternative names
- A530055J10 antibody
- alpha-E1 antibody
- alpha-M290 antibody
see all
Images
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BALB/c mesenteric lymph node cells were first labeled with ab25211 at 0.1 µg/106 cells, and then double-stained with streptavidin-FITC and rat anti-mouse CD8a-R-PE (ab25498). Small lymphocytes were gated and analyzed on a FACScan flow cytometer (BDIS, San Jose, CA).
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab25211 has been referenced in 1 publication.
- Lefrançois L et al. Developmental expression of the alpha IEL beta 7 integrin on T cell receptor gamma delta and T cell receptor alpha beta T cells. Eur J Immunol 24:635-40 (1994). PubMed: 7907296