Product nameAnti-Integrin alpha V antibody
See all Integrin alpha V primary antibodies
DescriptionRabbit polyclonal to Integrin alpha V
Tested applicationsSuitable for: WB, IHC-P, ICCmore details
Species reactivityReacts with: Rat, Human
Predicted to work with: Mouse
Synthetic peptide corresponding to Human Integrin alpha V (C terminal).
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferPreservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab112487 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 116 kDa.|
|IHC-P||Use a concentration of 1 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.|
|ICC||Use a concentration of 1 µg/ml.|
FunctionThe alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Sequence similaritiesBelongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
- Information by UniProt
- antigen identified by monoclonal antibody L230 antibody
- CD 51 antibody
- CD51 antibody
All lanes : Anti-Integrin alpha V antibody (ab112487)
Lane 1 : Rat spleen tissue lysate
Lane 2 : Rat pancreas tissue lysate
Lane 3 : Rat brain tissue lysate
Lane 4 : Rat liver tissue lysate
Lane 5 : MM231 whole cell lysate
Lane 6 : HeLa whole cell lysate
Lane 7 : CEM whole cell lysate
Lane 8 : Colo320 whole cell lysate
Predicted band size: 116 kDa
Observed band size: 116 kDa
ab112493 staining CD51 in breast cancer by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Detection by ABC/DAB staining.
ab112487 has not yet been referenced specifically in any publications.