Key features and details
- Rabbit polyclonal to Integrin alpha V
- Suitable for: WB, ELISA, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Integrin alpha V antibody
See all Integrin alpha V primary antibodies
DescriptionRabbit polyclonal to Integrin alpha V
Tested applicationsSuitable for: WB, ELISA, IHC-Pmore details
Species reactivityReacts with: Human
Synthetic peptide conjugated to KLH corresponding to C terminal residues of Human Integrin alpha V (NP_002201.1).
- Human Placenta and Thyroid tissues; A549 cell extracts, treated with etoposide.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 0.88% Sodium chloride, 50% Glycerol
PBS (without Mg2+, Ca2+)
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab117611 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Predicted molecular weight: 116 kDa.|
|IHC-P||Use a concentration of 5 µg/ml.|
FunctionThe alpha-V integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Sequence similaritiesBelongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
- Information by UniProt
- antigen identified by monoclonal antibody L230 antibody
- CD 51 antibody
- CD51 antibody
ab117611, at 5 µg/ml, staining Integrin alpha V in Formalin-fixed, Paraffin-embedded Human Thyroid tissue by Immunohistochemistry.
ab117611, at 5 µg/ml, staining Integrin alpha V in Formalin-fixed, Paraffin-embedded Human Placenta tissue by Immunohistochemistry.
All lanes : Anti-Integrin alpha V antibody (ab117611) at 1/500 dilution
Lane 1 : A549 cell extracts, treated with etoposide 25uM 1hr
Lane 2 : A549 cell extracts, treated with etoposide 25uM 1h with synthetic peptide
Predicted band size: 116 kDa
ab117611 has been referenced in 3 publications.
- Spinelli C et al. Molecular subtypes and differentiation programmes of glioma stem cells as determinants of extracellular vesicle profiles and endothelial cell-stimulating activities. J Extracell Vesicles 7:1490144 (2018). PubMed: 30034643
- Vogt D et al. Premacular membranes in tissue culture. Graefes Arch Clin Exp Ophthalmol N/A:N/A (2018). PubMed: 29931427
- Hoshino A et al. Tumour exosome integrins determine organotropic metastasis. Nature 527:329-35 (2015). WB ; Human . PubMed: 26524530