Key features and details
- Potent, adenosine kinase inhibitor
- CAS Number: 24386-93-4
- Purity: > 95%
- Soluble in DMSO to 50 mM
- Form / State: Solid
- Source: Synthetic
Product nameIodotubercidin, adenosine kinase inhibitor
DescriptionPotent, adenosine kinase inhibitor
Potent, specific adenosine kinase inhibitor (IC50 = 26 nM). Inhibits platelet aggregation and spreading, and interferes with adenosine and adenine nucleotide metabolism. Additionally inhibits other kinases such as ERK2 (Ki = 525 nM).
Storage instructionsStore at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Solubility overviewSoluble in DMSO to 50 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
- Pathways and Processes
- Metabolic signaling pathways
- Energy transfer pathways
- Energy Metabolism
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab120452 has been referenced in 1 publication.
- Huang L et al. Enhanced expression of WD repeat-containing protein 35 via CaMKK/AMPK activation in bupivacaine-treated Neuro2a cells. PLoS One 9:e98185 (2014). PubMed: 24859235