Overview

  • Product name

    Iohexol, contrast agent for imaging
  • Description

    Non-ionic monomeric triiodinated x-ray contrast agent
  • Biological description

    Non-ionic monomeric triiodinated x-ray contrast agent. Density gradient medium to measure hemodynamic parameters in vivo. Induces apoptosis. Orally active.
  • Purity

    > 98%
  • CAS Number

    66108-95-0
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    5-[Acetyl(2,3-dihydroxypropyl)amino]-1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodobenzene-1,3-dicarboxamide
  • Molecular weight

    821.14
  • Molecular formula

    C19H26I3N3O9
  • PubChem identifier

    3730
  • Storage instructions

    Store at Room Temperature. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in water to 100 mM
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    CC(=O)N(CC(CO)O)C1=C(C(=C(C(=C1I)C(=O)NCC(CO)O)I)C(=O)NCC(CO)O)I
  • Source

    Synthetic

  • Research areas

References

This product has been referenced in:

  • Jost G  et al. Dynamic contrast-enhanced computed tomography to assess antitumor treatment effects: comparison of two contrast agents with different pharmacokinetics. Invest Radiol 48:715-21 (2013). Read more (PubMed: 23666093) »
  • Collignon CM  et al. Comparison of pharmacokinetic variables for creatinine and iohexol in dogs with various degrees of renal function. Am J Vet Res 73:1841-7 (2012). Read more (PubMed: 23106473) »
  • Gong X  et al. N-acetylcysteine amide protects renal proximal tubular epithelial cells against iohexol-induced apoptosis by blocking p38 MAPK and iNOS signaling. Am J Nephrol 31:178-88 (2010). Read more (PubMed: 20016144) »

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