• Product name

    Anti-Ionotropic glutamate receptor 2 + 3 antibody
    See all Ionotropic glutamate receptor 2 + 3 primary antibodies
  • Description

    Rabbit polyclonal to Ionotropic glutamate receptor 2 + 3
  • Host species

  • Tested applications

    Suitable for: IHC-FoFr, WB, IP, IHC-Pmore details
  • Species reactivity

    Reacts with: Pigeon, Human
    Predicted to work with: Mouse, Rat, Bird, Monkey
  • Immunogen

    Synthetic peptide within Human Ionotropic glutamate receptor 2 + 3 aa 850 to the C-terminus (C terminal). The exact sequence is proprietary.
    Database link: P42262

  • Positive control

    • Cerebellum



Our Abpromise guarantee covers the use of ab27225 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-FoFr Use at an assay dependent concentration. PubMed: 20674673
WB Use at an assay dependent concentration. Predicted molecular weight: 96 kDa.
IP Use at an assay dependent concentration.
IHC-P 1/50. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.


  • Relevance

    Ion channels activated by glutamate are typically divided into two classes. Those sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by a-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). AMPAR are comprised of four distinct Glutamate Receptor Subunits (GluR1-4) and they play key roles in almost all excitatory neurotransmission in the brain. The GluR2 subunit is widely expressed throughout the nervous system where it is thought to play key roles in synaptic plasticity and learning and memory.
  • Cellular localization

    Cell Membrane; multi-pass membrane protein.
  • Database links

  • Alternative names

    • AMPA selective glutamate receptor 2 antibody
    • AMPA selective glutamate receptor 3 antibody
    • GluR K2 antibody
    • GluR K3 antibody
    • GLURB antibody
    • GLURC antibody
    • GLUTAMATE RECEPTOR 2 antibody
    • GLUTAMATE RECEPTOR 3 antibody
    • Glutamate receptor ionotropic AMPA 2 antibody
    • Glutamate receptor ionotropic AMPA 3 antibody
    • GRIA2 antibody
    • GRIA3 antibody
    see all


  • Ab27225 at a dilution of 1/50, staining ionotropic Glutamate Receptor 2+3 in Human cerebellum by Immunohistochemistry (formalin fixed, paraffin embedded sections).


This product has been referenced in:

  • Ripka S  et al. Glutamate receptor GRIA3--target of CUX1 and mediator of tumor progression in pancreatic cancer. Neoplasia 12:659-67 (2010). IHC-P ; Human . Read more (PubMed: 20689760) »
  • Cabral AL  et al. GluR2/3 label expression of the AMPA-type glutamate receptor in the hippocampal formation of the homing pigeon stabilizes just after birth. Neurosci Lett 483:73-7 (2010). IHC-FoFr, WB ; Pigeon . Read more (PubMed: 20674673) »
See all 2 Publications for this product

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