Overview

Properties

Applications

Our Abpromise guarantee covers the use of ab7206 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/5000.

Target

  • Function
    Chemotactic for monocytes and T-lymphocytes. Binds to CXCR3.
  • Sequence similarities
    Belongs to the intercrine alpha (chemokine CxC) family.
  • Post-translational
    modifications
    CXCL10(1-73) is produced by proteolytic cleavage after secretion from keratinocytes.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • Interferon gamma induced factor MOB1, mouse, homolog of antibody
    • Interferon gamma induced protein 10 antibody
    • 10 kDa interferon gamma induced protein antibody
    • 10 kDa interferon gamma-induced protein antibody
    • C X C motif chemokine 10 antibody
    • C7 antibody
    • Chemokine (C X C motif) ligand 10 antibody
    • Chemokine CXC motif ligand 10 antibody
    • Crg 2 antibody
    • CRG2 antibody
    • CXCL10 antibody
    • CXCL10(1-73) antibody
    • CXL10_HUMAN antibody
    • Gamma IP10 antibody
    • Gamma-IP10 antibody
    • gIP 10 antibody
    • GIP10 antibody
    • IFI10 antibody
    • INP 10 antibody
    • INP10 antibody
    • Interferon activated gene 10 antibody
    • Interferon activated gene 10 antibody
    • Interferon gamma induced cell line antibody
    • Interferon inducible cytokine IP 10 antibody
    • Interferon inducible cytokine IP10 antibody
    • IP 10 antibody
    • IP-10 antibody
    • Mob 1 antibody
    • MOB1 antibody
    • Protein 10 from interferon (gamma) induced cell line antibody
    • SCYB10 antibody
    • Small inducible cytokine B10 antibody
    • Small inducible cytokine B10 precursor antibody
    • Small inducible cytokine subfamily B (Cys X Cys) member 10 antibody
    • Small inducible cytokine subfamily B CXC member 10 antibody
    • Small inducible cytokine subfamily B, member 10 antibody
    • Small-inducible cytokine B10 antibody
    see all

References

This product has been referenced in:
  • Ji Y  et al. Angiotensin II induces inflammatory response partly via toll-like receptor 4-dependent signaling pathway in vascular smooth muscle cells. Cell Physiol Biochem 23:265-76 (2009). WB ; Rat . Read more (PubMed: 19471094) »
See 1 Publication for this product

Customer reviews and Q&As

1-2 of 2 Abreviews or Q&A

Answer

For ab112521: DISCOUNT CODE:***

For ab7206: DISCOUNT CODE: ***

For ab79044: DISCOUNT CODE: ***

For ab133173: DISCOUNT CODE: ***

For ab43773: DISCOUNT CODE: ***

For ab90181: DISCOUNT CODE:***

Expiration date: January 11th, 2013

I am very pleased to hear you would like to accept our offer and testthese antibodies for use in IHC-FoFr on rat samples.Each code will give you: 1 freeprimary antibodybefore the expiration date. To redeem this offer, please submit an Abreview forIHC-FoFr on ratand include this code in the “Additional Comments” section so we know the Abreview is for this promotion. Please remember that submission of the Abreview is sufficient for the discount code to become active.
For more information on how to submit an Abreview, please visit the site: https://www.abcam.com/Abreviews.

Remember, we publish both positive and negative Abreviews on our datasheets so please submit the results of your tests. The code will be active once the Abreview has been submitted and can be redeemed in one of the following ways: 1) Call to place your order and mention the code to our customer service department; 2) Include the code in your fax order; 3) Place your order on the web and enter the promotional code.

Any feedback that you can provide will be greatly appreciated, whether positive or negative. If you have any further questions, please do not hesitate to contact us. We look forward to receiving your Abreview and wish you luck with your research.

The terms and conditions applicable to this offer can be found here: https://www.abcam.com/collaborationdiscount.

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Question
Answer

Thank you for your enquiry and for taking your time to fill in the on-line Questionnaire and forwarding the images. Could we remind you that ab7206 is a polyclonal antibody and it may recognize different epitopes. Even the scanned Western blot image on our website shows non-specific bands. According to the Swiss-Prot datasheet, the expected band size is 10,73 kDa which is not that different from what the customer sees on the blot at around 13 kDa. There are disulfide sites along the peptide chain at positions 30 and 32 which may suggest some potential post-translational modifications. These may be good binding sites for other SH-containing molecules which can potentially create cross-links with the protein and alter the predicted molecular weight (although this is just prediction). Does the customer use pre-stained markers? If so, than the coupling of the chromophore to the polypeptide chains can actually affect the electrophoretic mobility in SDS-gel ELFO so it is not advisable to use the markers for quantitave studies (only for qualitative tools to determine approximate size). The antibody has been tested and characterized for Western blot application using rat brain lysate but rat spleen can also be used as good positive control. We hope this will help. If there is any doubt about the specificity of this particular antibody, then please get back to me.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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